Korean J Obstet Gynecol.  2009 Aug;52(8):815-820.

The prevalence and risk factors of lower limb lymphedema in the patients with gynecologic neoplasms

Affiliations
  • 1Department of Physical Medicine and Rehabilitation, Dong-eui Hospital, Busan, Korea.
  • 2Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan, Korea. leehula@hanmail.net
  • 3Department of Obstetrics and Gynecology, Kosin University College of Medicine, Busan, Korea.

Abstract


OBJECTIVE
To identify the prevalence and risk factors for lower limb lymphedema in the patients after gynecologic neoplasms treatment in Korea.
METHODS
We retrospectively reviewed the medical records and interviewed 242 gynecologic neoplasms patients who have managed surgically and medically over a 4 year period between January 2003 and December 2006. We identified the patients with lower limb lymphedema as described by the medical records or reported by the interviews. We obtained demographic characteristics, other medical history, cancer type, stage of cancer, lymph node dissection, chemotherapy, radiotherapy, hormone therapy and laboratory findings. Multiple logistic regression analysis was done to evaluate the risk factors for lower limb lymphedema.
RESULTS
Forty eight (19.8%) patients out of two hundred forty two had lower limb lymphedema. Those patients with lower limb lymphedema had a higher body mass index, radiotherapy history, chemotherapy history and lymph node dissection history, radical hysterectomy. Multivariate analysis revealed that body mass index, radiotherapy and lymph node dissection were independently risk factors for lower limb lymphedema after gynecologic neoplasms treatment.
CONCLUSION
The patients who had radiotherapy, body mass index greater than 25 or lymph node dissection must be considered as potential candidates to have lower limb lymphedema in the patients after gynecologic neoplasms treatment. Therefore, these patients should be informed during the follow-up period about this morbidity, the preventive measures, and the treatments.

Keyword

Lymphedema; Gynecologic neoplasms; Risk factor

MeSH Terms

Body Mass Index
Female
Follow-Up Studies
Genital Neoplasms, Female
Humans
Hysterectomy
Korea
Logistic Models
Lower Extremity
Lymph Node Excision
Lymphedema
Medical Records
Multivariate Analysis
Prevalence
Retrospective Studies
Risk Factors
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