Korean J Hepatobiliary Pancreat Surg.  2009 Jun;13(2):120-123.

Collision Tumor of the Liver (Hepatocellular Carcinoma and Undifferentiated Sarcoma)

• Seo HI

Abstract

Collision tumors represent the coexistence of two adjacent but histologically distinct tumors in an organ. Collision tumors have been identified in various organs, but they are rare in liver. We present a rare case of a 57-year-old man, who was hospitalized for the removal of a liver mass (S5/6 segmentectomy), that was probably a hepatocellular carcinoma. The eventual pathology examination revealed a collision tumor composed of a hepatocellular carcinoma and an undifferentiated sarcoma. Because the tumor recurred 2 months after the operation, reoperation (right hemicolectomy and tumorectomy) was performed. In the 2nd month following the second operation we found multiple liver metastases, chest metastasis and abdominal cavity metastasis. To our knowledge this is the first case of a hepatic collision tumor that was composed of a hepatocellular carcinoma and an undifferentiated sarcoma. Herein, we report the case of a hepatic collision tumor and briefly review the literature.

Keyword

Collision tumor; Hepatocellular carcinoma; Sarcoma

MeSH Terms

Abdominal Cavity
Carcinoma, Hepatocellular
Humans
Liver
Middle Aged
Neoplasm Metastasis
Reoperation
Sarcoma
Thorax