Gut Liver.
2009 Jun;3(2):141-144. 10.5009/gnl.2009.3.2.141.
A Case of Acute Q Fever with Severe Acute Cholestatic Hepatitis
- Affiliations
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- 1Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. gidoctor@korea.com, gidoctor@snubh.org
- 2Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
- KMID: 1464760
- DOI: http://doi.org/10.5009/gnl.2009.3.2.141
Abstract
- Minimal hepatic dysfunction can be common in acute Q fever, but severe acute cholestatic hepatitis is rarely reported. We report on a 55-year-old male with acute Q fever and severe acute cholestatic hepatitis. He complained of fever, jaundice, ascites, and restlessness on admission. A liver biopsy revealed the presence of compact fibrin-ring granulomas. Serologic titers for C. burnetii IgM and IgG were 2048:1 and 1024:1, respectively. C. burnetii DNA was detected by a nested polymerase chain reaction on the liver tissue.
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