Korean J Gastrointest Endosc.  2010 Mar;40(3):203-208.

Eosinophilic Colitis Presenting with Bloody Diarrhea: Case Report

• Jang SI
• Park HY
• Jun IS

Abstract

Eosinophilic colitis is a chronic inflammatory bowel condition of unknown etiology and a rare subtype of eosinophilic gastrointestinal diseases. It is characterized by gastrointestinal symptoms and increased eosinophil numbers in the intestinal mucosa and absence of other potential causes of gastrointestinal eosinophilia. The clinical presentation is varied and depends on the involved layer of the large intestine. There are no confirmatory laboratory tests, and the morphologic evaluation of biopsies or surgical specimens is required to confirm the diagnosis. A 65-year-old man presented with an 8 day duration of bloody diarrhea and lower abdominal pain. The patient was diagnosed with eosinophilic colitis by histopathological evaluation of biopsies and was further categorized as a nonatopic variant associated with non-IgE-mediated reaction. The patient was successfully treated with systemic corticosteroid for 2 weeks. On follow-up after 9 months, the patient remained well without relapse or new lesions.

Keyword

Eosinophilic colitis; Bloody diarrhea; Nonatopic variant

MeSH Terms

Abdominal Pain
Aged
Biopsy
Colitis
Diarrhea
Eosinophilia
Eosinophils
Follow-Up Studies
Gastrointestinal Diseases
Humans
Intestinal Mucosa
Intestine, Large
Recurrence