J Korean Soc Ultrasound Med.  2010 Sep;29(3):147-151.

Langerhans Cell Histiocytosis Arising from the Mandible as Diagnosed by US-guided Core Biopsy

Affiliations
  • 1Department of Radiology, Center of Thyroid Cancer, National Cancer Center, Gyeonggi-do, Korea.
  • 2Department of Radiology, Research Institute of Radiological Science, Yonsei University Heath System, Seoul, Korea. ekkim@yuhs.ac
  • 3Department of Internal Medicine, Eulji University College of Medicine, Eulji University Hospital, Daejeon, Korea.

Abstract

Langerhans cell histiocytosis (LCH) is a clonal proliferative disorder of Langerhans cells. Although LCH is not considered a malignant disease, its appearance on radiographs may be similar to that of a malignant tumor. The diagnosis of LCH is usually made by a soft tissue biopsy, or by bone marrow aspiration or curettage. We present a patient with a mandibular mass confirmed to be LCH by US-guided core needle biopsy, and present a strategy for diagnosing localized LCH of the bone based on the usefulness and reliability of the percutaneous biopsy.

Keyword

Langerhans cell histiocytosis; Mandibular mass; Eosinophillic granuloma on mandible; US-guided core needle biopsy; Bone mass

MeSH Terms

Biopsy
Biopsy, Large-Core Needle
Bone Marrow
Curettage
Histiocytosis, Langerhans-Cell
Humans
Langerhans Cells
Mandible
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