Korean J Dermatol.  2011 May;49(5):483-486.

Generalized Discoid Lupus Erythematosus Occurring in a Systemic Lupus Erythematosus Patient

• Sim HS
• Jung SY
• Lee HJ
• Seo JK
• Lee D
• Sung HS

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multisystem involvement. Skin is the second most frequently affected organ in SLE, and various forms of cutaneous LE (CLE), such as acute, subacute, and chronic CLE, are observed in higher than 75% of patients with SLE. Discoid LE (DLE) is the most common form of chronic CLE, and a small subset of patients with SLE also has concomitant DLE. A 32-year-old woman diagnosed with SLE 6 years ago visited our clinic with a 2-month history of multiple hyperpigmented macules and patches over the entire body. She also complained of arthralgia, auditory, and visual hallucinations. Her clinical presentation, laboratory findings, and histopathologic features were consistent with generalized DLE and aggravation of her SLE. Herein, we report an unusual case of generalized DLE occurring in a patient with SLE.

Keyword

Discoid lupus erythematosus; Generalized; Systemic lupus erythematosus

MeSH Terms

Adult
Arthralgia
Autoimmune Diseases
Female
Hallucinations
Humans
Lupus Erythematosus, Discoid
Lupus Erythematosus, Systemic
Skin