J Korean Soc Ultrasound Med.  2012 Jun;31(2):87-91.

Role of Ultrasound Volume Measurements of Testes in Evaluation of Infertile Men with Azoospermia

• Moon MH
• Seo JT
• Chun YK
• Sung CK
• Cho JY
• Kim SH

Abstract

PURPOSE
The purpose of our study was to assess the usefulness of ultrasounddetermined testicular volume in the evaluation of the infertile men with azoospermia.
MATERIALS AND METHODS
A computerized search from October 2005 to June 2010 generated a list of 45 infertile men with azoospermia (mean age, 34 years; age range, 26-44 years) who underwent both scrotal ultrasound and testis biopsy. Ultrasounddetermined testicular volumes were compared between infertile men with obstructive azoospermia and those with non-obstructive azoospermia.
RESULTS
Testicular volume for obstructive azoospermia ranged from 6.4 ml to 26.9 ml, with a median volume of 14.0 ml. This volume was significantly larger than that of those with non-obstructive azoospermia, which ranged from 1.0 ml to 12.8 ml, with a median volume of 6.1 ml (p < 0.001). The area under the ROC curve for distinguishing non-obstructive azoospermia from obstructive azoospermia using testicular volume was 0.91. A cutoff value of less than or equal to 11.4 ml could distinguish non-obstructive azoospermia from obstructive azoospermia, with a sensitivity of 94.1% (95% CI; 71.3-99.9%) and a specificity of 73.3% (95% CI; 54.1-87.7%).
CONCLUSION
Ultrasound-determined testicular volume can be helpful in the differentiation of obstructive azoospermia from non-obstructive azoospermia.

Keyword

Ultrasonography; Testis; Azoospermia

MeSH Terms

Azoospermia
Biopsy
Humans
Male
ROC Curve
Sensitivity and Specificity
Testis