J Korean Soc Radiol.  2012 Oct;67(4):235-239. 10.3348/jksr.2012.67.4.235.

Imaging Features and Sonographically Guided Core-Needle Biopsy of Facial Myopericytoma: A Case Report

• Lee SK
• Kwon SY

• KMID: 1439532
• DOI: http://doi.org/10.3348/jksr.2012.67.4.235

Abstract

We report imaging and pathologic findings of myopericytoma of the face, in a 75-year-old woman, which was diagnosed by a sonographically guided core-needle biopsy (US-CNB). The mass was well-demarcated and intensely enhanced on a CT scan and was markedly hypervascular on a power Doppler ultrasonography. Histological findings of the specimens, obtained by US-CNB, were consistent with myopericytoma. While myopericytoma of the face appears markedly hypervascular on imaging, the histological diagnosis can be established safely with US-CNB, without significant bleeding, if sufficient manual compression is applied.

MeSH Terms

Aged
Biopsy
Biopsy, Needle
Female
Hemorrhage
Humans
Tomography, X-Ray Computed
Ultrasonography, Doppler

Figure

• 

  Fig. 1 Myopericytoma of the face, diagnosed by sonographically guided core-needle biopsy (US-CNB), in a 75-year-old woman. A. A non-enhanced CT image shows an ovoid mass (arrows) at the left lower face adjacent to the mandibular body. The mass is slightly hypoattenuating compared with the sternocleidomastoid muscle. B. A contrast-enhanced CT image reveals homogeneous, intense enhancement (as intense enhancement as vascular structures) of the mass (arrows). C. A gray-scale sonographic image shows a well-demarcated, homogeneous, and markedly hypoechoic solid mass (arrows), adjacent to the mandibular body (arrowhead). D. A power Doppler sonographic image reveals marked hypervascularity of the mass. E. A photomicrograph of low-power view of the specimen obtained by US-CNB of the mass reveals distinctive multilayered, concentric, perivascular arrangement of the spindle-shaped cells around the blood vessels (arrows) (Hematoxylin & Eosin staining, × 40). F. The immunohistochemical staining of the specimen, obtained by US-CNB, for smooth muscle actin (SMA) reveals diffuse and strong immunoreactivity of the perivascular myoid cells (SMA, × 200).

Reference

1. Granter SR, Badizadegan K, Fletcher CD. Myofibromatosis in adults, glomangiopericytoma, and myopericytoma: a spectrum of tumors showing perivascular myoid differentiation. Am J Surg Pathol. 1998. 22:513–525.

2. Gengler C, Guillou L. Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology. 2006. 48:63–74.

3. Mentzel T, Dei Tos AP, Sapi Z, Kutzner H. Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases. Am J Surg Pathol. 2006. 30:104–113.

4. McMenamin ME, Fletcher CD. Malignant myopericytoma: expanding the spectrum of tumours with myopericytic differentiation. Histopathology. 2002. 41:450–460.

5. Dray MS, McCarthy SW, Palmer AA, Bonar SF, Stalley PD, Marjoniemi V, et al. Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases. J Clin Pathol. 2006. 59:67–73.

6. Lee SK, Kwon SY. Gray-scale and power Doppler sonography and CT findings of myopericytoma of the posterior cervical space. AJNR Am J Neuroradiol. 2009. 30:1604–1606.

7. Chu ZG, Yu JQ, Yang ZG, Zhu ZY, Yuan HM. Myopericytoma involving the parotid gland as depicted on multidetector CT. Korean J Radiol. 2009. 10:398–401.

8. Rho BH, Lee SK, Kwon SY. Myopericytoma of the neck: sonographic appearance and sonographically guided needle biopsy. J Clin Ultrasound. 2011. 39:469–472.

9. Zimmermann KW. Der feinere Bau der Blutcapillaren. Z Anat Entwicklungsgesch. 1923. 68:29–109.

10. Laga AC, Tajirian AL, Islam MN, Bhattacharyya I, Cohen DM, Plamondon CJ, et al. Myopericytoma: report of two cases associated with trauma. J Cutan Pathol. 2008. 35:866–870.