J Korean Soc Radiol.  2012 Mar;66(3):267-270. 10.3348/jksr.2012.66.3.267.

Schwannomatosis with Cystic Degeneration Arising from a Single Intercostal Nerve: A Case Report

Affiliations
  • 1Department of Radiology, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea. ykradio@medimail.co.kr
  • 2Department of Thoracic & Cardiovascular Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea.
  • 3Department of Radiology, Kyung Hee Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.

Abstract

An intrathoracic schwannoma is a benign neurogenic tumor that arises from the posterior mediastinum and is commonly found to be solitary. Schwannomatosis that manifests as multiple cysts is extremely rare. In this case study, we report a rare case of a 36-year-old man with no respiratory symptoms, with multiple cystic tumors in the posterior chest wall and pathologically confirmed schwannomatosis with cystic degeneration arising from a single intercostal nerve.


MeSH Terms

Adult
Humans
Intercostal Nerves
Mediastinum
Neurilemmoma
Neurofibromatoses
Skin Neoplasms
Thoracic Wall
Neurilemmoma
Neurofibromatoses
Skin Neoplasms

Reference

1. Weiss SW, Goldblum JR. Enzinger and Weiss's soft tissue tumors. 2001. 4th ed. St. Louis: Mosby;1146–1167.
2. McClenathan JH, Bloom RJ. Peripheral tumors of the intercostal nerves. Ann Thorac Surg. 2004. 78:713–714.
3. Chen F, Nakayama E, Okubo K, Date H. Intrathoracic multiple schwannomas of a single intercostal nerve. Ann Thorac Surg. 2008. 86:660–661.
4. Lee JW, Hsu JY. Schwannomatosis of a single intercostal nerve: a case report. Kaohsiung J Med Sci. 2009. 25:405–408.
5. Jacoby LB, Jones D, Davis K, Kronn D, Short MP, Gusella J, et al. Molecular analysis of the NF2 tumor-suppressor gene in schwannomatosis. Am J Hum Genet. 1997. 61:1293–1302.
6. Hulsebos TJ, Plomp AS, Wolterman RA, Robanus-Maandag EC, Baas F, Wesseling P. Germline mutation of INI1/SMARCB1 in familial schwannomatosis. Am J Hum Genet. 2007. 80:805–810.
7. Choi YW. Radiological findings of pleural and mediastinal diseases. Tuberc Respir Dis. 2005. 58:543–553.
8. Ishida T, Maruyama R, Saitoh G, Mitsudomi T, Sugimachi K. Thoracoscopy in the management of intrathoracic neurogenic tumors. Int Surg. 1996. 81:347–349.
9. Davidson KG, Walbaum PR, McCormack RJ. Intrathoracic neural tumours. Thorax. 1978. 33:359–367.
Full Text Links
  • JKSR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr