J Korean Med Assoc.  2012 Aug;55(8):779-790. 10.5124/jkma.2012.55.8.779.

Management of adverse reaction to iodinated radiocontrast media

Affiliations
  • 1Department of Radiology, Asan Medical Center, University of Ulan College of Medicine, Seoul, Korea. mjshin@amc.seoul.kr
  • 2Department of Internal Medicine, Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea.

Abstract

Application of iodinated radiographic contrast media (RCM) has increased recently because of the number of computed tomography examinations using RCM is increasing rapidly. The awareness regarding potential adverse reactions due to contrast media and the necessary precautions to be taken is of utmost importance both for radiologists and referring physicians since the adverse reactions including hypersensitivity reactions to RCM are still unpredictable and reported in significantly increasing number among exposed patients year by year. In 2011, Korean guideline for the safe use of RCM was published by the Korean Society of Radiology and Korean Academy of Asthma, Allergy and Clinical Immunology. On behalf of these organizations a committee named Korean Network of Allergists & Radiologists for Research of Radio-contrast Media-associated Adverse Reactions (KOAR3A) was formed and collaborated to develop guidelines. Its major purpose is to provide a clinically practical and evidence-based manual full of useful information regarding patient screening, premedication, recognition of adverse reactions, and emergency treatment of such reactions in daily practice as well as other problems, especially kidney toxicity and endocrine problems in consultation with the corresponding medical specialists.

Keyword

Radiocontrast media; Injection, intravenous; Computed tomography; Adverse drug reaction; Hypersensitivity

MeSH Terms

Asthma
Contrast Media
Drug Toxicity
Emergency Treatment
Humans
Hypersensitivity
Injections, Intravenous
Kidney
Mass Screening
Premedication
Specialization
Contrast Media

Figure

  • Figure 1 Intramuscular injection site: anterolateral aspect of mid-thigh.


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Radiocontrast media hypersensitivity in the Asia Pacific region
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