J Korean Soc Transplant.  2012 Mar;26(1):15-22. 10.4285/jkstn.2012.26.1.15.

The Quality of Life for Living Donors after Kidney Transplantation

• Kim MH
• Kwon OJ
• Kang CM

• KMID: 1435078
• DOI: http://doi.org/10.4285/jkstn.2012.26.1.15

Abstract

BACKGROUND
The impact on quality of life (QOL) and safety has increasingly been an important consideration for living donors after kidney transplantation. The purposes of this study were to evaluate the QOL of living kidney donors and to indentify factors for impediment of their QOL.
METHODS
The subjects of this study were 69 living kidney donors with whom transplantations were performed in our center from 1990 to 2010. The data was collected from May to July 2010 using donor characteristics and SF-36.
RESULTS
The donors were predominantly female (60.9%) and the average age was 45.4+/-12.0 years. The total numbers of donors, categorized by their relationship to the recipients, included 20 siblings (29.0%), 17 parents (24.6%) and 13 spouses (18.8%). The measured characteristics as related to donation included the full return to normal pre-donation activities (72.5%), no visit to a hospital or pharmacy after donation (69.6%) and donation decision as propria persona (97.1%). Most donors were satisfied with their donation (92.8%) and had no regrets for making the donation (87.0%). The average score for QOL of all subjects was 71.89. The overall QOL of living kidney donors revealed lower scores (48.56+/-5.45) as compared to average scores (50) of the healthy population in the USA. In particular, the scores for PCS (52.87) on the SF-36 were higher than the scores for MCS (44.25).
CONCLUSIONS
Most living kidney donors were satisfied with their donation and showed good physical recoveries despite a lower QOL. Consequently, carefully pre-transplantation psychological assessment and programs are necessary to support donors. Systematic and continuous management after transplantation, as well as preoperatively appropriate information and counsel, is needed for kidney donors.

Keyword

QOL; Kidney transplantation; Living donor

MeSH Terms

Female
Humans
Kidney
Kidney Transplantation
Living Donors
Parents
Pharmacy
Quality of Life
Siblings
Spouses
Tissue Donors
Transplants

Reference

1. Korean Network for Organ Sharing (KONOS). 2010 KONOS Annual Report [Internet]. 2010. Seoul: KONOS;Available from: http://konos.go.kr.

2. Johnson EM, Anderson JK, Jacobs C, Suh G, Humar A, Suhr BD, et al. Long-term follow-up of living donors: quality of life after donation. Transplantation. 1999. 67:717–721.

3. Ku JH. Health-related quality of life of living kidney donors: review of the short form 36-health questionnaire survey. Transpl Int. 2005. 18:1309–1317.

4. Lumsdaine JA, Wray A, Power MJ, Jamieson NV, Akyol M, Andrew Bradley J, et al. Higher quality of life in living donor kidney transplantation: prospective cohort study. Transpl Int. 2005. 18:975–980.

5. Shrestha A, Shrestha A, Basarab-Horwath C, McKane W, Shrestha B, Raftery A. Quality of life following live donor renal transplantation: a single centre experience. Ann Transplant. 2010. 15:5–10.

6. Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992. 30:473–483.

7. Kim KS, Kang JY, Jeong IS. Health related quality of life among organ transplant recipients. J Korean Acad Nurs. 2003. 33:365–375.

8. Mjøen G, Stavem K, Westlie L, Midtvedt K, Fauchald P, Norby G, et al. Quality of life in kidney donors. Am J Transplant. 2011. 11:1315–1319.

9. Lima DX, Petroianu A, Hauter HL. Quality of life and surgical complications of kidney donors in the late post-operative period in Brazil. Nephrol Dial Transplant. 2006. 21:3238–3242.

10. Conrad M, Wahrman J, Williams S, Jorkasky D. Living related donation: a sibling controlled study. Transplant Proc. 1987. 19:1492–1493.

11. Levey AS, Hou S, Bush HL Jr. Kidney transplantation from unrelated living donors. Time to reclaim a discarded opportunity. N Engl J Med. 1986. 314:914–916.

12. Liounis B, Roy LP, Thompson JF, May J, Sheil AG. The living related kidney donor: a follow-up study. Med J Aust. 1988. 148:436–437. 440–444.

13. Sterner K, Zelikovsky N, Green C, Kaplan BS. Psychosocial evaluation of candidates for living related kidney donation. Pediatr Nephrol. 2006. 21:1357–1363.

14. Franklin PM, Crombie AK. Live related renal transplantation: psychological, social and cultural issues. Transplantation. 2003. 76:1247–1252.

15. Johnson EM, Remucal MJ, Gillingham KJ, Dahms RA, Najarian JS, Matas AJ. Complications and risks of living donor nephrectomy. Transplantation. 1997. 64:1124–1128.

16. Hilhorst MT. Directed altruistic living organ donation: partial but not unfair. Ethical Theory Moral Pract. 2005. 8:197–215.

17. Fehrman-Ekholm I, Duner F, Brink B, Tydén G, Elinder CG. No evidence of accelerated loss of kidney function in living kidney donors: results from a cross-sectional follow-up. Transplantation. 2001. 72:444–449.

18. Lamanna MA. Giving and getting: altruism and exchange in transplantation. J Med Humanit. 1997. 18:169–192.

19. Jordan J, Sann U, Janton A, Gossmann J, Kramer W, Kachel HG, et al. Living kidney donors' long-term psychological status and health behavior after nephrectomy-a retrospective study. J Nephrol. 2004. 17:728–735.

20. Reimer J, Rensing A, Haasen C, Philipp T, Pietruck F, Franke GH. The impact of living related kidney transplantation on the donor's life. Transplantation. 2006. 81:1268–1273.