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J Korean Soc Transplant.  2010 Jun;24(2):80-86. 10.4285/jkstn.2010.24.2.80.

Safety for Expanding Living-Donor Criteria in Renal Transplantation

Affiliations
  • 1Division of Nephrology, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. alterego54@catholic.ac.kr

Abstract

The increasing waiting times for deceased donor kidneys have focused attention on living donors as a useful way to increase the organ supply. However, living donors with potential medical risks for renal transplantation raise medical and ethical questions for donor nephrectomy about conditions such as hypertension, hematuria, obesity, and old age. Data on the long-term risks of conditions are sparse and potential acceptance criteria are under development. Many older donors hope to donate to their offspring, despite the presence of elevated blood pressure. Transplant professionals have internal debates on these situations that require a well-defined scoring system for donating risk. This review summarizes the characteristics and risk of marginal living donors in renal transplantation and discusses strategies for overcoming the current limitation.

Keyword

Living donors; Safety; Hypertension; Hematuria; Obesity; Old age; Renal transplantation

MeSH Terms

Blood Pressure
Hematuria
Humans
Hypertension
Kidney
Kidney Transplantation
Living Donors
Nephrectomy
Obesity
Tissue Donors
Transplants
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