Dement Neurocogn Disord.  2013 Jun;12(2):56-59. 10.12779/dnd.2013.12.2.56.

A Case of Meningoencephalitis due to Relapsing Polychondritis Presenting Cognitive Impairment; Serial Neuropsychological Tests

• MoeMoe AC
• Kim TE
• Kim HJ
• Park SA

• KMID: 1432266
• DOI: http://doi.org/10.12779/dnd.2013.12.2.56

Abstract

Central nervous system involvement by relapsing polychondritis is rare. Despite the fact that several reports described its cognitive presentations, the detailed neuropsychological characteristics have not been provided. Severe cognitive impairment was noted in our patient with meningoencephalitis due to polychondiritis. With immunosuppressant therapy, his deficits recovered markedly, but not completely in some severely affected cognitive domains from the earlier time. Neuropsychological complications of polychondritis are very responsive to immunosuppressants although it does not seem to be perfect.

Keyword

Cognition; Meningoencephalitis; Polychondritis

MeSH Terms

Central Nervous System
Cognition
Humans
Immunosuppressive Agents
Meningoencephalitis
Neuropsychological Tests
Polychondritis, Relapsing
Immunosuppressive Agents

Figure

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  Fig. 1 The electroencephalogram (EEG) findings. (A) The initial EEG taken on 5th hospital day shows frequent bilateral frontal rhythmic sharp and slow waves complexes. (B) With steroid therapy follow up EEG was taken on 20th hospital day, which demonstrates intermittent diffuse semirhythmic bifrontal dominant delta slowings. (C) The last EEG was checked five months after the admission, which reveals no abnormal findings.

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