Dement Neurocogn Disord.  2013 Jun;12(2):52-55. 10.12779/dnd.2013.12.2.52.

Hypersomnia as Presenting Symptom in Wilson's Disease

• Jang JW
• Park SY
• Park YH
• Yun CH
• Kim JE
• Kim S

• KMID: 1432265
• DOI: http://doi.org/10.12779/dnd.2013.12.2.52

Abstract

Wilson's disease shows considerably various symptoms that sometimes timely diagnosis is delayed when patient shows vague clinical presentation. We present a female patient whose initial symptom was hypersomnia and severe fatigue. She was initially diagnosed as depression. Because initial hepatic function test was unremarkable, it was not easy to come to think about relationship between hepatic function and hypersomnia. Her final diagnosis was Wilson's disease. This case suggested that hypersomnia otherwise unexplained could be the presenting symptom of Wilson's disease.

Keyword

Wilson's disease; Hypersomnia; Hepatic dysfunction

MeSH Terms

Depression
Disorders of Excessive Somnolence
Fatigue
Female
Hepatolenticular Degeneration
Humans

Figure

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  Fig. 1 Liver CT of the patient. Large amount of ascites and moderate to severe degree of fatty liver with hepatomegaly was observed.

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  Fig. 2 Brain MRI of the patient. Subtle T1-weighed high signal intensity at bilateral globus pallidus.

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