Korean J Ophthalmol.  2012 Oct;26(5):391-393. 10.3341/kjo.2012.26.5.391.

A Case of Idiopathic Central Serous Chorioretinopathy in a 12-year-old Male Treated with Bevacizumab

• Kim YC
• Kim SD
• Kim KS

• KMID: 1397492
• DOI: http://doi.org/10.3341/kjo.2012.26.5.391

Abstract

A 12-year-old male presented with a chief complaint of a 1-month-history of decreased visual acuity in his right eye. The patient had no past history of steroid use or other systemic diseases. On fundus examination, which included fluorescent angiography (FAG) and optical coherence tomography (OCT), the patient was diagnosed with idiopathic central chorioretinopathy, whose clinical course was monitored without any specific treatments. At the time of admission, the best-corrected visual acuity was 0.5 in the right eye and 1.0 in the left eye. On fundoscopy, a serous detachment of 1 disc diameter in size was observed in the posterior pole. According to the FAG and the OCT, serous neurosensory detachment was present. After two months of monitoring the clinical course, the best corrected visual acuity in the right eye was 0.8, and there was improvement of neurosensory retinal detachment. However, OCT detected recurrence after five months, and the corrected visual acuity was decreased to 0.6. Bevacizumab was then injected into the vitreous cavity. Complete resolution of the subretinal fluid resulted eight months later, and the corrected visual acuity improved to 1.0.

Keyword

Bevacizumab; Central serous chorioretinopathy; Pediatrics

MeSH Terms

Angiogenesis Inhibitors/*therapeutic use
Antibodies, Monoclonal, Humanized/*therapeutic use
Central Serous Chorioretinopathy/diagnosis/*drug therapy
Child
Fluorescein Angiography
Humans
Male
Ophthalmoscopy
Tomography, Optical Coherence
Visual Acuity

Figure

• 

  Fig. 1 (A) A fundus photograph of the right eye shows a 1-disc-diameter, well circumscribed collection of subretinal fluid at the posterior pole (arrow). (B) The filling phase of fluorescein angiography (FAG) shows pinpoint dye leakage (arrow). (C) The late phase of the FAG shows spread of the dye and filling of the detached area (arrow head).

• 

  Fig. 2 (A) Optical coherence tomography (OCT) at the time of the first visit shows serous neurosensory retinal detachment (asterisk). (B) OCT two months later shows nearly resolved subretinal serous fluid.

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