Yonsei Med J.  2006 Oct;47(5):755-758. 10.3349/ymj.2006.47.5.755.

A Giant Colonic Hamartoma and Multiple Colonic Hamartomatous Polyps in a Middle-Aged Man

• Park IJ
• Kim HC
• Yu CS
• Koo HL
• Kim JS
• Kim JC

• KMID: 1381261
• DOI: http://doi.org/10.3349/ymj.2006.47.5.755

Abstract

Colonic hamartomas are rare polypoid lesions. We report an unusual case of multiple colonic hamartomatous polyps, including a giant hamartoma, unrelated to hereditary or familial polyposis syndromes, in a 48-year-old man. The diameter of the largest polyp was 9.5 cm, and endoscopy revealed that the lesion caused colonic obstruction. The clinical, endoscopic and histological aspects of this case are discussed.

Keyword

Hamartoma; giant hamartoma

MeSH Terms

Middle Aged
Male
Intestinal Obstruction/*pathology/surgery
Humans
Hamartoma/*pathology/surgery
Colonoscopy
Colonic Polyps/*pathology/surgery
Colonic Diseases/*pathology/surgery
Colectomy

Figure

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  Fig. 1 Colonoscopy showing multiple polyps in the descending colon. (A) A large obstructing mass in the proximal descending colon. (B, C, D) Multiple lobular polyps.

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  Fig. 2 Gross colon specimen showing multiple polyps. (A) Six polyps were identified along the entire colon. (B) A 5-cm polyp was identified in the ascending colon. (C) A 12.5 × 9 × 5 cm multi-lobular broad-based polypoid mass with numerous mulberry-like projections in the proximal descending colon. (D) Cut surface showing no proliferative mucosa.

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  Fig. 3 (A) The stromal core composed of disorganized bundles of smooth muscle, and the intact mucosal surface (scanning view). (B, C) Colonic-type mucosa composed of distorted branching crypts supported by cores of smooth muscle originating from the muscularis mucosa (H & E: × 100). (D) The junction of the stromal core and the mucosa showing disorganization of the muscularis mucosae with smooth muscle extension into crypts (H & E: × 200).

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