J Korean Med Sci.  2000 Aug;15(4):467-470. 10.3346/jkms.2000.15.4.467.

Hamartomatous gastric polyposis in a patient with tuberous sclerosis

• Kim BK
• Kim YI
• Kim WH

• KMID: 1730648
• DOI: http://doi.org/10.3346/jkms.2000.15.4.467

Abstract

A 42-year-old female diagnosed with tuberous sclerosis was found to have multiple polyps in the fundus of stomach. On histologic examination, the lesions were hamartomatous polyps. In tuberous sclerosis, many lesions occur in multiple organs and there are several reports about the frequent association of hamartomatous polyps of the colon. However, gastric manifestation of tuberous sclerosis has not been established probably due to its asymptomatic nature. This is the first report of multiple gastric hamartomatous polyposis in patient with tuberous sclerosis.

Keyword

Tuberous Sclerosis; Polyps; Stomach; Hamartoma

MeSH Terms

Abdominal Pain/etiology
Actins/analysis
Adult
Case Report
Cecal Neoplasms/pathology
Encephalomalacia/etiology
Female
Gastric Fundus/pathology
Gastroscopy
Hamartoma/genetics+ACo-
Human
Hyperplasia
Nasopharyngeal Neoplasms/pathology
Neoplasm Proteins/analysis
Polyps/genetics+ACo-
Protein Isoforms/analysis
Stomach Neoplasms/genetics+ACo-
Tuberous Sclerosis/pathology+ACo-
Tumor Markers, Biological/analysis