Tuberc Respir Dis.  2002 Aug;53(2):196-201. 10.4046/trd.2002.53.2.196.

A Case of Unknown Primary Malignant Melanoma with Pulmonary and Endobronchial Metastasis

• Min YH
• Kim SW
• Chin HJ
• Lee TY
• Song HH
• Lee KS
• Lee JA
• Park YL
• Hyun IG

• KMID: 1320435
• DOI: http://doi.org/10.4046/trd.2002.53.2.196

Abstract

Malignant melanoma is a highly malignant form of cutaneous cancer derived from melanocytes. The lesion frequently metastasizes to the lymph nodes, lung, liver and bone. However, an endobronchial metastasis and a primary malignant melanoma of the lung are quite rare. We report a case of an unknown primary malignant melanoma with a pulmonary and endobronchial metastasis in a 34 years old male. He complained of coughing and black-colored sputum. Abnormal skin and mucosal lesions were not found during a physical examination. A chest X-ray revealed multiple nodular masses in both lung fields. A flexible bronchoscopy showed two yellowish small nodules at the entry of left lower bronchus. Vimentin, the S-100 protein, and HMB-45 stain positive melanoma cells were detected at the bronchoscopic biopsy specimen.

Keyword

Malignant melanoma; Endobronchial metastasis

MeSH Terms

Biopsy
Neoplasm Metastasis