Korean J Pathol.
2008 Aug;42(4):236-239.
Massive Perivillous Fibrin Deposition in Placenta
- Affiliations
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- 1Department of Pathology, University of Ulsan College of Medicine, Gangneung, Korea. edwjyh@gnah.co.kr
- 2Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Gangneung, Korea.
Abstract
- Massive perivillous fibrin deposition (MFD) is a rare condition characterized by heavy accumulation of fibrin in intervillous or perivillous spaces encasing villi throughout the placenta. This condition may cause varying degrees of placental insufficiency, leading to a significantly increased risk of intrauterine growth retardation, intrauterine death, and pre-term delivery. However, the objective criteria for the diagnosis of MFD have not been clearly established. We report a case of MFD associated with intrauterine growth retardation and preterm premature rupture of membranes.
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