J Korean Med Sci.
2000 Jun;15(3):355-358. 10.3346/jkms.2000.15.3.355.
Isolated splenic metastasis from colorectal carcinoma: a case report
- Affiliations
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- 1Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. jckim@www.amc.seoul.kr
- KMID: 1128638
- DOI: http://doi.org/10.3346/jkms.2000.15.3.355
Abstract
- Isolated splenic metastasis arising from colorectal carcinoma is very rare and there has been only 6 cases reported in the English literature. A new case is esented, and its possible pathogenesis was considered with previously reported ses. A 65-year-old male patient had received a right hemicolectomy for cending colon cancer 36 months earlier. He was followed up regularly with rial measurement of serum carcinoembryonic antigen (CEA). Rising serum CEA was scovered from 33 months postoperatively and CT revealed an isolated splenic tastasis. He therefore underwent splenectomy, which was proven to be a tastatic adenocarcinoma with similar histological feature to the original mor. As all reported cases showed elevated serum CEA at the time of tastasis, isolated splenic metastasis might be associated with CEA in regard its biological functions of immunosuppression and adhesion.
MeSH Terms
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Adenocarcinoma/surgery
Adenocarcinoma/secondary*
Adenocarcinoma/pathology
Adenocarcinoma/blood
Aged
Carcinoembryonic Antigen/blood
Case Report
Colorectal Neoplasms/surgery
Colorectal Neoplasms/pathology*
Colorectal Neoplasms/blood
Human
Male
Splenic Neoplasms/surgery
Splenic Neoplasms/secondary*
Splenic Neoplasms/blood
Tomography Scanners, X-Ray Computed
