Yonsei Med J.  1991 Mar;32(1):79-81. 10.3349/ymj.1991.32.1.79.

Two cases of nickel dermatitis showing vitiligo-like depigmentations

Affiliations
  • 1Department Microbiology, Ajou Univ College of Med, Suwon, Korea.
  • 2Department Dermatology, Ajou Univ College of Med, Suwon, Korea.
  • 3Duck Hyun Kim's Dermatology Clinic, Seoul, Korea.
  • 4Department of Dermatology, Capital Armed Forces General Hospital, Seoul, Korea.
  • 5Department of Pediatrics, Seoul National Univ College Med, Seoul, Korea.

Abstract

The authors reviewed two patients showing "vitiligo-like depigmentations" where the skin had been in close contact with a metal spectacle frame made of nickel alloy. In spite of the hypersensitivity to nickel in both patients, they showed clinical and histologic findings indicate that the formation of "vitiligo-like depigmentation" does not result from posinflammatory hypopigmentation but from chemical hypomelanosis. We could not explain the underlying mechanisms; however, the speculation that the "vitiligo-like depigmentation" may come from the direct effect of the nickel itself, prompted us to report these cases.

Keyword

Nickel dermatitis; vitiligo-like depigmentation; nickel sensitivity

MeSH Terms

Adult
Dermatitis, Contact/*etiology
Human
Male
Middle Aged
Nickel/*adverse effects
Vitiligo/*chemically induced
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