Korean J Gastroenterol.  2008 Mar;51(3):174-180.

Efficacy of Endoscopic Resection for Small Rectal Carcinoid: A Retrospective Study

• Kim YJ
• Lee SK
• Cheon JH
• Kim TI
• Lee YC
• Kim WH
• Chung JB
• Yi SW
• Park S

Abstract

BACKGROUND/AIMS
Well differentiated rectal carcinoid tumors which are less than 1cm in diameter can be treated by endoscopic resection. We aimed to evaluate the efficacy of endoscopic resection in treating small sized rectal carcinoids.
METHODS
Medical records of 30 rectal carcinoid cases treated by endoscopic resection in Yonsei University College of Medicine, Severance Hospital between January 1995 and March 2007 were reviewed retrospectively.
RESULTS
Mean age was 49.7 years and male to female ratio was 1:0.88. Mean size of tumor was 6.29+/-3.06 mm and 25 out of 30 patients (83.3%) had tumors of diameter less than 10 mm. Twenty-two out of 30 patients treated by conventional polypectomy, 6 by endoscopic mucosal resection using a transparent cap (EMR-C) and 2 by endoscopic submucosal dissection (ESD). Histological examination revealed that 9 patients had resection margin positive for tumor; 7 (31.8%) were in polypectomy group, 1 (16.7%) in EMR-C group, and 1 (50%) in ESD group (p=0.868). Five patients underwent transanal excision to remove residual tumor. No residual tumor was found in additionally resected tissue. Mean follow-up duration was 19. 3 months (range 0-122), and there were no recurrence.
CONCLUSIONS
Endoscopic resection is an effective method in the treatment of small rectal carcinoids. However, long-term outcome remains to be elucidated by a large scaled prospective study.

Keyword

Carcinoid, Rectum; Polypectomy; Endoscopic mucosal resection using a transparent cap; Endoscopic submucosal dissection

MeSH Terms

Adult
Aged
Carcinoid Tumor/pathology/*surgery/therapy
Demography
*Endoscopy, Gastrointestinal
Female
Follow-Up Studies
Humans
Male
*Microsurgery
Middle Aged
Rectal Neoplasms/pathology/*surgery/therapy
Retrospective Studies
Treatment Outcome