Korean J Gastroenterol.
2007 Apr;49(4):245-250.
Metachronous Gastric MALT Lymphoma and Early Gastric Cancer: A Case Report
- Affiliations
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- 1Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. kskwon@inha.ac.kr
- 2Center for Advanced Medical Education, Inha University Collage of Medicine by BK-21 Project, Incheon, Korea.
- 3Department of Pathology, Inha University College of Medicine, Incheon, Korea.
Abstract
- Metachronous association between gastric lymphoma and early gastric cancer is a rare event. Recent studies have suggested that a relationship exists between gastric mucosa-associated lymphoid tissue (MALT) lymphoma and gastric carcinoma although the mechanism is unknown. Herein, we report a 53-year-old man who visited to our hospital due to melena. Esophagogastroduodenoscopy (EGD) revealed a MALT lymphoma on the greater curvature of lower body. The patient received anti-Helicobacter pylori eradication therapy, followed by 6 cycles of chemotherapy and radiation therapy, and achieved complete remission 12 months after the therapy. Three years later, he revisited our hospital with epigastric pain. EGD revealed an early gastric cancer on the anterior wall of proximal antrum, nearly opposite to the previous lymphoma site, and a partial gastrectomy was performed. To the best of our knowledge, this is the first case report of metachronous MALT lymphoma and subsequent gastric carcinoma in Korea.
MeSH Terms
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Anti-Bacterial Agents/therapeutic use
Endoscopy, Digestive System
Gastric Mucosa/*pathology
Helicobacter Infections/drug therapy
Helicobacter pylori
Humans
Lymphoma, B-Cell, Marginal Zone/*diagnosis/pathology/radiotherapy
Male
Middle Aged
Neoplasms, Second Primary/*diagnosis/etiology
Stomach Neoplasms/*diagnosis/pathology
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