J Vet Sci.  2010 Jun;11(2):173-175. 10.4142/jvs.2010.11.2.173.

Autologous conditioned plasma as therapy of tendon and ligament lesions in seven horses

Affiliations
  • 1Equine Clinic, Faculty of Veterinary Medicine, Freie Universita Berlin, Oertzenweg 19b, 14163 Berlin, Germany.
  • 2Institute for Biometrics and Data Processing, Faculty of Veterinary Medicine, Freie Universitat Berlin, Oertzenweg 19b, 14163 Berlin, Germany.
  • 3Department for Large Animal Diseases, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 100, 02-786 Warsaw, Poland.

Abstract

This case report describes the intralesional application of autologous conditioned plasma (ACP) in seven horses as treatment of severe tendinitis of the superficial digital flexor tendon, deep digital flexor tendon, or desmitis of the inferior check ligament. Follow-up data of the horses revealed a positive outcome in 10 to 13 months post injury. All horses treated with ACP were either performing in their previous work-load or were back in full training. Further studies with long-term follow-up will have to be performed to support these clinical intermediate-term observations.

Keyword

autologous conditioned plasma; horse; regenerative therapy; tendon

MeSH Terms

Animals
Blood Component Transfusion/*veterinary
Female
Horses/*injuries
Ligaments/*injuries/pathology
Male
*Platelet-Rich Plasma
Tendinopathy/pathology/therapy/*veterinary

Figure

  • Fig. 1 The percentage of the maximum injury zone compared to the healthy tendon/ligament (%MIZ) of the superficial digital flexor tendon (SDFT; n = 6 limbs), deep digital flexor tendon (DDFT; n = 1 limb) and inferior check ligament (ICL; n = 1 limb) at day 0 (D0), D1 and D2 in seven horses. D0: day of presentation, D1: two to three weeks after D0, D2: two to three weeks after D1. SDFT 3A and SDFT 3B: different forelimbs of the same horse.

  • Fig. 2 The cross sectional area (CSA) of superficial digital flexor tendon (SDFT; n = 6 limbs), deep digital flexor tendon (DDFT; n = 1 limb) and inferior check ligament (ICL; n = 1 limb) at D0, D1 and D2 in seven horses. D0: day of presentation, D1: two to three weeks after D0, D2: two to three weeks after D1. SDFT 3A and SDFT 3B: different forelimbs of the same horse.


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