Korean J Parasitol.  2010 Dec;48(4):331-333. 10.3347/kjp.2010.48.4.331.

Experimental Toxocara cati Infection in Gerbils and Rats

Affiliations
  • 1Department of Parasitology and Mycology, School of Medicine, Lorestan University of Medical Sciences, Khorram Abad, Iran. zibaeim@sums.ac.ir
  • 2Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • 3Department of Parasitology, Faculty of Health Sciences, Kobe University Graduate School of Health Sciences, Kobe, Japan.

Abstract

Mongolian gerbils and Wistar rats were inoculated orally with 240 and 2,500 Toxocara cati embryonated eggs, respectively, to evaluate the larval recovery in different tissues and organs, such as the liver, lungs, heart, kidney, and skeletal muscles after 5, 30, 49, 70, and 92 days post-infection (PI). Larval recovery rates were 1.7-30.0% in Mongolian gerbils on days 5-92 PI and 0.2-3.8% in rats on the same days. These results indicate that Mongolian gerbils and Wistar rats are suitable experimental paratenic hosts for the study of neurological toxocariasis as well as visceral toxocariasis.

Keyword

Toxocara cati; Mongolian gerbil; Wistar rat; experimental infection

MeSH Terms

Animal Structures/parasitology
Animals
*Disease Models, Animal
Gerbillinae
Histocytochemistry
Male
Microscopy
Rats
Rats, Wistar
Toxocara/*pathogenicity
Toxocariasis/*parasitology/*pathology
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