Korean J Radiol.  2011 Dec;12(6):761-764. 10.3348/kjr.2011.12.6.761.

A Rare Case of Epiphyseal Chondromyxoid Fibroma of the Proximal Tibia

• Choi YS
• Kim BS
• Joo JE
• Park YK
• Lee SH
• Song BY

• KMID: 1101934
• DOI: http://doi.org/10.3348/kjr.2011.12.6.761

Abstract

Chondromyxoid fibroma is an uncommon benign cartilaginous tumor of the bone. It occurs most frequently in the metaphysis of long tubular bones, and an epiphyseal location is exceedingly rare. We present here an unusual case of a chondromyxoid fibroma that occurred in the epiphysis of the proximal tibia with an open growth plate. MR imaging findings of this tumor, which has, to the best of our knowledge, never been described in an epiphyseal location, makes the present case unique.

Keyword

Chondromyxoid fibroma; Bone, tumors; Epiphysis; Magnetic Resonance Imaging (MRI)

MeSH Terms

Adolescent
Bone Neoplasms/*diagnosis
Chondroma/*diagnosis
Epiphyses
Fibroma/*diagnosis
Humans
Magnetic Resonance Imaging
Male
*Tibia

Figure

• 

  Fig. 1 Epiphyseal chondromyxoid fibroma in 15-year-old boy. A, B. Oblique (A) and lateral (B) roentgenograms of left knee show well-defined, radiolucent lesion with thin rim of sclerosis (arrows) in anterior epiphysis of proximal tibia. C. Coronal T1-weighted image shows lobulated, heterogeneously low signal intensity lesion in epiphysis of tibia. D, E. Lesion shows slightly high signal intensity with hypointense peripheral rim on coronal proton-density image (D) and high signal intensity on sagittal fat-suppression T2-weighted fast spin echo image (E). Hypointense foci (arrows) in E are suspicious of calcifications. F. Coronal postcontrast T1-weighted image shows inhomogeneous enhancement of lesion. G. Photomicrograph of lesion shows macrolobular growth patterns with multinucleated giant cells at periphery of lobules (Hematoxylin & Eosin staining, × 200). H. Photomicrograph shows lobular growth pattern with hypercellularity at periphery of lobule and low cellular myxoid stroma at center of lobule (Hematoxylin & Eosin staining, × 200). I. Higher magnification of periphery of lobule shows multinucleated giant cells and myxoid stroma. Some cells show hyaline cartilage differentiation (Hematoxylin & Eosin staining, × 400).

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