Korean J Lab Med.  2011 Jan;31(1):47-48. 10.3343/kjlm.2011.31.1.47.

Bacteremia Caused by Corynebacterium amycolatum with a Novel Mutation in gyrA Gene that Confers High-Level Quinolone Resistance

• Yoon S
• Kim H
• Lee Y
• Kim S

• KMID: 1096660
• DOI: http://doi.org/10.3343/kjlm.2011.31.1.47

Abstract

Although Corynebacterium amycolatum can cause opportunistic infections, it is commonly considered as contaminant. In this report, we present a case of bacteremia caused by C. amycolatum with a novel mutation in the gyrA gene that confers high-level quinolone resistance to the organism.

Keyword

Corynebacterium amycolatum; gyrA mutation; Quinolone resistance

MeSH Terms

Aged, 80 and over
Anti-Bacterial Agents/*pharmacology
Bacteremia/*microbiology
Corynebacterium/drug effects/*genetics/isolation & purification
Corynebacterium Infections/*diagnosis/drug therapy
DNA Gyrase/*genetics
Drug Resistance, Bacterial/genetics
Fluoroquinolones/*pharmacology
Humans
Male
Microbial Sensitivity Tests
Mutation
Vancomycin/therapeutic use

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