Korean J Intern Med.
2007 Jun;22(2):113-117. 10.3904/kjim.2007.22.2.113.
Castleman Disease Presenting with Jaundice: A Case with the Multicentric Hyaline Vascular Variant
- Affiliations
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- 1Department of Internal Medicine, Seoul National University College of Medicine1, Seoul, Korea.
- 2Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. smbang7@snu.ac.kr
- 3Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
- 4Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.
- 5Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
- KMID: 1091872
- DOI: http://doi.org/10.3904/kjim.2007.22.2.113
Abstract
- Castleman disease (CD) is a rare lymphoproliferative disorder of unknown etiology with different clinical manifestations. A previous healthy 50 year-old man was hospitalized for right upper quadrant (RUQ) abdominal pain. He had jaundice and a 1 cm-sized lymph node in the right supraclavicular area. Pancreas and biliary computed tomography (CT) showed masses at the right renal hilum and peripancreatic areas. Positron emission tomography (PET) showed widespread systemic lymphadenopathy. Excisional biopsy of the right supraclavicular node revealed a hyaline vascular variant of CD. Corticosteroid therapy was started and the extent of disease decreased. We here report a case of multicentric CD, the hyaline vascular variant, presenting with jaundice, diagnosed by excisional biopsy and successfully treated with corticosteroids.
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