Korean J Parasitol.  2011 Jun;49(2):167-171. 10.3347/kjp.2011.49.2.167.

Clinical Features of Ocular Toxoplasmosis in Korean Patients

• Park YH
• Han JH
• Nam HW

• KMID: 1090617
• DOI: http://doi.org/10.3347/kjp.2011.49.2.167

Abstract

We report here the records of 10 consecutive Korean patients (10 eyes) with ocular toxoplasmosis which showed the typical clinical manifestations with seropositivity for Toxoplasma gondii specific IgG antibodies by micro-ELISA between 2006 and 2010. Nine patients were males and 1 was female; their age was 50.5+/-13.8 years. The most common accompanying signs were vitritis (100%), anterior uveitis (70%), and scattered white deposit (80%). Pre-existing retinochoroidal scar was found in 1 (10%) patient. All patients received antiparasitic chemotherapy and systemic corticosteroid treatment, which resolved the presenting attack and recovered the visual acuity better than initial one in 9 patients and worse in 1. Optic atrophy, cataract, and retinal neovascularization were observed during the follow-up period and recurrence was detected in 3 eyes (30%) 6 to 20 months after the initial attack. In Korea, although rarely detected and reported, ocular toxoplasmosis needs more attention in clinical field of retinal diseases.

Keyword

Toxoplasma gondii; toxoplasmosis; retinochoroiditis; funduscopy; IgG-ELISA

MeSH Terms

Adrenal Cortex Hormones/administration & dosage
Adult
Age Distribution
Aged
Anti-Inflammatory Agents/administration & dosage
Antibodies, Protozoan/*blood
Antiprotozoal Agents/administration & dosage
Cataract/pathology
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immunoglobulin G/blood
Korea
Male
Middle Aged
Optic Atrophy/pathology
Retinal Neovascularization/pathology
Sex Distribution
Toxoplasma/immunology/*isolation & purification
Toxoplasmosis, Ocular/complications/*diagnosis/drug therapy/*pathology
Uveitis, Anterior/complications/drug therapy/parasitology/pathology