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Clusters of Toxoplasmosis in Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea

Yu J, Kim W, Chang YK, Kim TS, Hong SJ, Ahn HJ, Nam HW, Kim D

We find out the clusters with high toxoplasmosis risk to discuss the geographical pattern in Gyodong-myeon and Samsan-myeon of Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea. Seroepidemiological data of toxoplasmosis surveyed using...
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Seroprevalence of Toxoplasma gondii assayed using Rapid Diagnostic Tests among Residents in Three Counties Adjacent to The Demilitarized Zone, Korea

Jung J, Lee J, Chang YK, Ahn SK, Park SH, Hong SJ, Lee J, Chong CK, Ahn HJ, Nam HW, Kim TS, Kim D

Toxoplasma gondii seroprevalence have been rapidly increasing in some parts of Korea. We analyzed prevalence of anti-Toxoplasma gondii antibodies, using a rapid diagnostic test (RDT), in the sera of 552...
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Secretome Analysis of Host Cells Infected with Toxoplasma gondii after Treatment of Human Epidermal Growth Factor Receptor 2/4 Inhibitors

Kim HJ, Ahn HJ, Kang H, Park J, Oh Sg, Choi S, Lee WK, Nam HW

Toxoplasma gondii, a ubiquitous, intracellular parasite of the phylum Apicomplexa, infects an estimated one-third of the human population as well as a broad range of warm-blooded animals. We have observed...
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Cluster of Parasite Infections by the Spatial Scan Analysis in Korea

Bae KE, Chang YK, Kim TS, Hong SJ, Ahn HJ, Nam HW, Kim D

This study was performed to find out the clusters with high parasite infection risk to discuss the geographical pattern. Clusters were detected using SatScan software, which is a statistical spatial...
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Clusters of Toxoplasmosis in Gyodong-Myeon and Samsan-Myeon, Ganghwa-Gun, Korea

Kim W, Chang YK, Kim TS, Hong SJ, Ahn HJ, Nam HW, Kim D

The purpose of this study is to find out the clusters with high toxoplasmosis risk to discuss the geographical pattern in 2 islands of Gyodong-myeon and Samsan-myeon in Ganghwa-gun, Korea....
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Detection of Human Anti-Trypanosoma cruzi Antibody with Recombinant Fragmented Ribosomal P Protein

Kim YH, Yang Z, Lee J, Ahn HJ, Chong CK, Maricondi , Dias RF, Nam HW

Chagas disease is caused by the protozoan parasite Trypanosoma cruzi, and is endemic in many Latin American countries. Diagnosis is based on serologic testing and the WHO recommends two or...
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Seroprevalence of Toxoplasma gondii among School Children in Pyin Oo Lwin and Naung Cho, Upper Myanmar

Thái TL, Jun H, Park SH, Lê HG, Lee J, Ahn SK, Kang JM, Myint MK, Lin K, Sohn WM, Nam HW, Na BK, Kim TS

Toxoplasma gondii is an apicomplexan parasite that can cause toxoplasmosis in a wide range of warm-blooded animals including humans. In this study, we analyzed seroprevalence of T. gondii among 467...
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Development and Clinical Evaluation of a Rapid Diagnostic Test for Yellow Fever Non-Structural Protein 1

Kim YH, Kim TY, Park JS, Park JS, Lee J, Moon J, Chong CK, Junior IN, Ferry FR, Ahn HJ, Bhatt L, Nam HW

A rapid diagnostic test (RDT) kit was developed to detect non-structural protein 1 (NS1) of yellow fever virus (YFV) using monoclonal antibody. NS1 protein was purified from the cultured YFV...
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Review of National Diagnostic Reference Levels for Interventional Procedures

Lee MY, Kwon J, Ryu GW, Kim KH, Nam HW, Kim KP

Diagnostic reference level (DRL) is employed to optimize the radiation doses of patients. The objective of this study is to review the DRLs for interventional procedures in Korea and abroad....
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Trends in the Diagnosis of Osteoporosis in Patients with Distal Radius Fractures Based on a National Claims Database

Kim DG, Seo GW, Nam HW

BACKGROUND: A history of osteoporotic fractures is strongly associated with the subsequent osteoporotic fractures. To prevent subsequent fractures, the diagnosis and treatment of osteoporosis following osteoporotic fractures are very important....
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Development of a Rapid Diagnostic Test Kit to Detect IgG/IgM Antibody against Zika Virus Using Monoclonal Antibodies to the Envelope and Non-structural Protein 1 of the Virus

Kim YH, Lee J, Kim YE, Chong CK, Pinchemel , Reisdörfer F, Coelho JB, Dias RF, Bae PK, Gusmão ZP, Ahn HJ, Nam HW

We developed a Rapid Diagnostic Test (RDT) kit for detecting IgG/IgM antibodies against Zika virus (ZIKV) using monoclonal antibodies to the envelope (E) and non-structural protein 1 (NS1) of ZIKV....
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Tissue Fluid Enzyme-Linked Immunosorbant Assay for Piglets Experimentally Infected with Toxoplasma gondii and Survey on Local and Imported Pork in Korean Retail Meat Markets

Yoo WG, Kim SM, Won EJ, Lee JY, Dai F, Woo HC, Nam HW, Kim TI, Han JH, Kwak D, Cho YS, Kang SW, Kim TS, Zhu XQ, Wang C, Youn H, Hong SJ

To investigate the prevalence of Toxoplasma gondii in pork on the market in Korea, an in-house enzyme-linked immunosorbent assay for tissue fluid (CAU-tf-ELISA) was developed using a soluble extract of...
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Seroprevalence of Toxoplasmosis Detected by RDT in Residents near the DMZ (demilitarized zone) of Cheorwon-gun, Gangwon-do, Korea

Kim YH, Lee J, Kim YE, Ahn S, Kim TS, Hong SJ, Chong CK, Ahn HJ, Nam HW

Seroprevalence of Toxoplasma gondii infection among the residents of Cheorwon-gun, Gangwon-do, Korea, which partly includes the demilitarized zone (DMZ), were surveyed for 4 years and evaluated by RDT using recombinant...
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Effects of Homocysteine and Hyperglycemia on the Proliferation of Aortic Vascular Smooth Muscle Cells of Obese Type 2 Diabetes Rat

Yoo HJ, Yu SH, Cho YJ, Nam HW, Kang DH

BACKGROUND: The aim of this study was to investigate the role of homocysteine on the proliferation of rat aortic vascular smooth muscle cells (VSMCs) by measuring mitogen-activated protein (MAP) kinase...
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Seroprevalence of Toxoplasmosis with ELISA and Rapid Diagnostic Test among Residents in Gyodong-do, Inchon city, Korea: A Four-Year Follow-up

Kim YH, Lee JH, Ahn SK, Kim TS, Hong SJ, Chong CK, Ahn HJ, Nam HW

ELISA has been used for the diagnosis of toxoplasmosis, but it is being gradually replaced by a rapid diagnostic test (RDT). We compared and analyzed ELISA and RDT results using...
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Comparison of Early and Late Tuberculosis Deaths in Korea

Lee J, Nam HW, Choi SH, Yoo SS, Lee SY, Cha SI, Park JY, Kim CH

The cause of death in patients with tuberculosis (TB) may differ according to the phase of anti-tuberculosis treatment. However, there are limited data regarding this issue in Korea. We compared...
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High Seroprevalence of Toxoplasmosis Detected by RDT among the Residents of Seokmo-do (Island) in Ganghwa-Gun, Incheon City, Korea

Kim YH, Lee J, Ahn S, Kim TS, Hong SJ, Chong CK, Ahn HJ, Nam HW

Seroprevalence of Toxoplasma gondii infection among the residents of Seokmo-do (Island) in Ganghwa-gun, Incheon, Korea was surveyed for 4 years by a rapid diagnostic test (RDT) using recombinant fragment of...
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Suppressors for Human Epidermal Growth Factor Receptor 2/4 (HER2/4): A New Family of Anti-Toxoplasmic Agents in ARPE-19 Cells

Kim YH, Bhatt L, Ahn HJ, Yang Z, Lee WK, Nam HW

The effects of tyrosine kinase inhibitors (TKIs) were evaluated on growth inhibition of intracellular Toxoplasma gondii in host ARPE-19 cells. The number of tachyzoites per parasitophorous vacuolar membrane (PVM) was...
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Western Blot Detection of Human Anti-Chikungunya Virus Antibody with Recombinant Envelope 2 Protein

Yang Z, Lee J, Ahn HJ, Chong CK, Dias RF, Nam HW

Chikungunya virus (CHIKV), a tropical pathogen, has re-emerged and has massive outbreaks abruptly all over the world. Containing many dominant epitopes, the envelope E2 protein of CHIKV has been explored...
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Afatinib Reduces STAT6 Signaling of Host ARPE-19 Cells Infected with Toxoplasma gondii

Yang Z, Ahn HJ, Park YH, Nam HW

Specific gene expressions of host cells by spontaneous STAT6 phosphorylation are major strategy for the survival of intracellular Toxoplasma gondii against parasiticidal events through STAT1 phosphorylation by infection provoked IFN-γ....
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