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Korean J Radiol.  2008 Aug;9(4):291-302. 10.3348/kjr.2008.9.4.291.

High-Intensity Focused Ultrasound Therapy: an Overview for Radiologists

Affiliations
  • 1Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. rhimhc@skku.edu
  • 2Department of Biomedical Engineering, College of Medicine, Cheju National University, Jeju-si, Korea.
  • 3Medical Physics Department, GSST & Division of Medical Imaging, Medical School, King's College London, University of London, UK.

Abstract

High-intensity focused ultrasound therapy is a novel, emerging, therapeutic modality that uses ultrasound waves, propagated through tissue media, as carriers of energy. This completely non-invasive technology has great potential for tumor ablation as well as hemostasis, thrombolysis and targeted drug/gene delivery. However, the application of this technology still has many drawbacks. It is expected that current obstacles to implementation will be resolved in the near future. In this review, we provide an overview of high-intensity focused ultrasound therapy from the basic physics to recent clinical studies with an interventional radiologist's perspective for the purpose of improving the general understanding of this cutting-edge technology as well as speculating on future developments.

Keyword

Interventional procedures, technology; Ultrasound (US), therapeutic; Ultrasound (US), focused; High-intensity focused ultrasound (HIFU)

MeSH Terms

Drug Delivery Systems
Gene Targeting
Hemostatic Techniques
Humans
Thrombolytic Therapy/methods
*Ultrasonic Therapy/methods
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