Korean J Gastroenterol.  2009 Feb;53(2):106-110.

Serial Episodes of Gastric and Cecal Perforation in a Patient with Behcet's Disease Involving the Whole Gastrointestinal Tract: A Case Report

• Shin DY
• Cheon JH
• Park JJ
• Kim H
• Kim TI
• Lee YC
• Kim NK
• Kim WH

Abstract

Behcet's disease (BD) has been recognized as multi-systemic chronic vasculitic disorder of recurrent inflammation, characterized by the involvement of multiple organs and resulting in orogenital ulcers, uveitis, and skin lesions. Involvement of the central nervous system, vessels, and intestines in BD often leads to a poor prognosis. Digestive manifestations in BD have been reported in up to 1-60% of cases, although the rate varies in different countries. The most frequent extra-oral sites of gastrointestinal involvement are the ileocecal region and the colon. Gastric or esophageal involvement is reported to be very rare. Moreover, there have been no reports on the simultaneous involvement of the esophagus, stomach, ileum, and colon. Here, we present a 55-year-old Korean man with intestinal BD and multiple ileal and colonic ulcerations complicated by perforation, gastric ulcer with bleeding followed by perforation, and esophageal ulcers with bleeding.

Keyword

Behcet's disease; Gastrointestinal; Ulcer; Perforation; Hemorrhage

MeSH Terms

Behcet Syndrome/complications/*diagnosis/pathology
Cecal Diseases/complications/pathology
Diagnosis, Differential
Endoscopy, Digestive System
Gastrointestinal Diseases/complications/*diagnosis
Gastrointestinal Hemorrhage
Humans
Intestinal Perforation/*diagnosis/etiology/pathology
Male
Middle Aged
Peptic Ulcer Perforation/pathology
Stomach Ulcer/complications/pathology