Korean J Parasitol.  2000 Dec;38(4):267-273. 10.3347/kjp.2000.38.4.267.

Five cases of ocular toxocariasis confirmed by serology

• Park SP
• Park I
• Park HY
• Lee SU
• Huh S
• Magnaval J

• KMID: 1057185
• DOI: http://doi.org/10.3347/kjp.2000.38.4.267

Abstract

We report 5 cases of ocular toxocariasis in Korean adults complaining of visual impairment along with floating or bubbling sensation. Fundoscopic examination revealed a retinal detachment along with exudate in 4 cases. They all showed typical reaction by ELISA and immunoblot against Toxocra excretory-secretory antigen. One case showed high level of anti-Toxocara IgE antibodies (34,000 Toxocara units/L) as well as increased level of serum total IgE antibodies and the specific IgE antibodies for 3 inhalant antigens, suggesting that high level of anti-Toxocara IgE antibodies was associated with an atopic status. Clinical manifestations were improved after the sequential use of steroids then mebendazole. We also suggest that ocular toxocariasis should be thoroughly investigated even when an evocative uniocular inflammatory lesion is encountered in peripheral retina without a systematic disease.

MeSH Terms

Adult
Aged
Animal
Antibodies, Protozoan/blood
Antigens, Protozoan/blood
Biological Markers/blood
Case Report
Enzyme-Linked Immunosorbent Assay
Female
Human
IgE/blood
Korea
Larva Migrans/diagnosis*
Male
Middle Age
Toxocara canis/immunology