- Sensory and motor axons are different: implications for neurological disease
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Burke D, Howells J, Kiernan MC
- KMID: 2367988
- Ann Clin Neurophysiol.
- 2017 Jan;19(1):3-12.
- doi: 10.14253/acn.2017.19.1.3
Using threshold tracking, differences have been established between large myelinated sensory and α motor axons in humans. Major differences are that sensory axons are relatively depolarised at rest such that... -
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- The Puzzling Case of Hyperexcitability in Amyotrophic Lateral Sclerosis
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Bae JS, Simon NG, Menon P, Vucic S, Kiernan MC
- KMID: 2179162
- J Clin Neurol.
- 2013 Apr;9(2):65-74.
- doi: 10.3988/jcn.2013.9.2.65
The development of hyperexcitability in amyotrophic lateral sclerosis (ALS) is a well-known phenomenon. Despite controversy as to the underlying mechanisms, cortical hyperexcitability appears to be closely related to the interplay... -
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- Dissociation of Structural and Functional Integrities of the Motor System in Amyotrophic Lateral Sclerosis and Behavioral-Variant Frontotemporal Dementia
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Bae JS, Ferguson M, Tan R, Mioshi E, Simon N, Burrell J, Vucic S, Hodges JR, Kiernan MC, Hornberger M
- KMID: 2354142
- J Clin Neurol.
- 2016 Apr;12(2):209-217.
- doi: 10.3988/jcn.2016.12.2.209
BACKGROUND AND PURPOSE: This study investigated the structural and functional changes in the motor system in amyotrophic lateral sclerosis (ALS; n=25) and behavioral-variant fronto-temporal dementia (bvFTD; n=17) relative to healthy... -
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