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Involvement of Src Family Tyrosine Kinase in Apoptosis of Human Neutrophils Induced by Protozoan Parasite Entamoeba histolytica

Sim S, Yu JR, Lee YA, Shin MH

Tyrosine kinases are one of the most important regulators for intracellular signal transduction related to inflammatory responses. However, there are no reports describing the effects of tyrosine kinases on neutrophil...
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Functional involvement of src and focal adhesion kinase in a CD99 splice variant-induced motility of human breast cancer cells.

Lee HJ, Kim ES, Jee BE, Hahn JH, Han KH, Jung KC, Park SH, Lee HS

  • KMID: 1380225
  • Exp Mol Med.
  • 2002 Jul;34(3):177-183.
Earlier report showed that expression of a splice variant of CD99 transmembrane protein increases invasive ability of human breast cancer cells. Cell motility was also significantly enhanced by the CD99...
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betaig-h3 triggers signaling pathways mediating adhesion and migration of vascular smooth muscle cells through alphavbeta5 integrin

Lee BH, Bae JS, Park RW, Kim JE, Park JY, Kim IS

  • KMID: 1111408
  • Exp Mol Med.
  • 2006 Apr;38(2):153-161.
Adhesion and migration of vascular smooth muscle cells (VSMCs) play an important role in the pathogenesis of atherosclerosis. These processes involve the interaction of VSMCs with extracellular matrix proteins. Here,...
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Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase

Sung DJ, Noh HJ, Kim JG, Park SW, Kim B, Cho H, Bae YM

  • KMID: 2154286
  • Exp Mol Med.
  • 2013 Dec;45(12):e67.
Serotonin (5-hydroxytryptamine (5-HT)) is a neurotransmitter that regulates a variety of functions in the nervous, gastrointestinal and cardiovascular systems. Despite such importance, 5-HT signaling pathways are not entirely clear. We...
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Signaling pathway for 2,3,7,8-tetrachlorodibenzo- p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages

Cheon HJ, Woo YS, Lee JY, Kim HS, Kim HJ, Cho S, Won NH, Sohn J

  • KMID: 756076
  • Exp Mol Med.
  • 2007 Aug;39(4):524-534.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a prototypic halogenated aromatic hydrocarbon (HAH), is known as one of the most potent toxicants. At least a part of its toxic effects appears to be derived from...
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