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Rab GTPases as Physiological Substrates of LRRK2 Kinase

Seol W, Nam D, Son I

LRRK2 (Leucine-Rich Repeat Kinase 2) is a gene whose specific mutations cause Parkinson's disease (PD), the most common neurodegenerative movement disorder. LRRK2 harbors GTPase and kinase activities, two enzyme activities...
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Membrane Trafficking of Collecting Duct Water Channel Protein AQP2 Regulated by Akt/AS160

Jung HJ, Kwon TH

  • KMID: 2406195
  • Electrolyte Blood Press.
  • 2010 Dec;8(2):59-65.
Akt (protein kinase B (PKB)) is a serine/threonine kinase that acts in the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway. The PI3K/Akt signaling pathway, triggered by growth factors and hormones including vasopressin,...
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