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Experimental meningoencephalitis by Naegleria fowleri in mice

Ahn MH, Im KI

Experimentally, primary amoebic meningoencephalitis (PAM) is induced by Naegleria fowleri in mouse and development of PAM may be influenced by the strain, weight and sex of mouse, and inoculum size...
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Ultrastructural observation of Naegleria fowleri trophozoite in mouse brain and axenic culture

Ryu JS, Soh CT, Im KI

Present study was undertaken to elucidate the changes of the ultrastructure of Naegleria fowleri trophozoite in brain tissue of mice and culture medium. Naegleria fowleri, 0359 strain, which used in...
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Effects of prednisolone injection on the liver of the mouse inoculated with the adult worms of Clonorchis sinensis intraperitoneally

Lee SH, Song CY, Chi JG

In order to understand the effect of prednisolone injection on the histopathological changes of the mouse liver and the chronological changes of the worm structure of Clonorchis sinensis, when this...
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Distribution of the larvae of Toxocara canis and Ascaris lumbricoides in the tissues of mice

Rim HJ

Mice were infected by feeding the embryonated eggs of Toxocara canis and Ascaris lumbricoides. Each mouse was killed daily for a week and then at several days interval after infection...
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Splitomicin, a SIRT1 Inhibitor, Enhances Hematopoietic Differentiation of Mouse Embryonic Stem Cells

Park JA, Park S, Park WY, Han MK, Lee Y

BACKGROUND AND OBJECTIVES: Embryonic stem (ES) cells have pluripotent ability to differentiate into multiple tissue lineages. SIRT1 is a class III histone deacetylase which modulates chromatin remodeling, gene silencing, cell...
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The host-parasite relations of Clonorchis sinensis in the mouse-Studies on the development of C. sinensis in mouse

Rhee CH, Seo BS

It is well established that guinea pig, rabbit and rat are equally susceptible to experimental infection with the Chinese liver fluke, Clonorchis sinensis. However, little work has been done on...
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Migration and distribution of spargana in body of experimentally infected mice

Choi WJ

The migration and distribution pattern of spargana in mouse body was observed after experimental infection through mouth. The spargana were obtained from the snake, Natrix tigrina lateralis, caught in Hoengseong-gun,...
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Immunological responses by soluble egg antigen of Schistosoma mansoni in mice

Ahn MH, Colley DG

This experiment shows cellular and humoral immune responses induced by soluble egg antigen of Schistosoma mansoni, that is, change of the number of peripheral blood eosinophil, delayed hypersensitivity measured by...
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Chemotherapeutic efficacy of trimethoprim-sulfamethoxazole (Bactrim) in experimental murine toxoplasmosis

Cho SW, Yong TS, Chung PR, Lee KT

The chemotherapeutic efficacy of trimethoprim-sulfamethoxazole (Bactrim) in mice experimentally infected with Toxoplasma gondii was evaluated. The average survival days and survival rate of mice infected intraperitoneally with 1 x 10(5)...
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Changes in the pathogenicity of Naegleria fowleri by several brain passage in mice

Lee DK, Lee KT, Im KI

The pathogenicity of free-living amoeba, Naegleria fowleri, is influenced according to the strain, cultural condition and host (Culbertson et al., 1968; Carter, 1970; Wong et al., 1975). Phillips (1973) demonstrated...
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Mitochondrial pyruvate dehydrogenase phosphatase 1 regulates the early differentiation of cardiomyocytes from mouse embryonic stem cells

Heo HJ, Kim HK, Youm JB, Cho SW, Song IS, Lee SY, Ko TH, Kim N, Ko KS, Rhee BD, Han J

Mitochondria are crucial for maintaining the properties of embryonic stem cells (ESCs) and for regulating their subsequent differentiation into diverse cell lineages, including cardiomyocytes. However, mitochondrial regulators that manage the...
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Studies on the comparative migration patterns of Ascaris suum larvae between primary and re-infected mice

Song JS, Kim JJ, Min DY, Lee KT

In the present study, the effect of primary infection to reinfection with Ascaris suum larvae was experimented in mouse model. Mice were challenged with l,000 infective stage eggs of Ascaris...
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Study on Metagonimus yokogawai(Katsurada, 1912) in Korea VII. Susceptibility of various strains of mice to Metagonimus infection and effect of Prednisolone

Chai JY, Seo BS, Lee SH

An experimental study was undertaken to observe the difference in susceptibility of mouse strains to Metagonimus yokogawai infection by estimating it from worm recovery rate and dimension of worms. It...
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Immunization effect on Naegleria fowleri infection in splenectomized mice

Han KH, Ahn MH, Min DY

A pathogenic free-living amoeba, Naegleria fowleri, is a causative protozoan parasite of primary amebic meningoencephalitis in human and experimental animals. It is known that humoral and cellular immunity contribute as...
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An experimental study on the pathogenicity of Korean strains of Trichomonas vaginalis

Song HC, Lee SH, Chi JG

In order to evaluate the pathogenicity of Korean strains of Trichomonas vaginalis, an experimental inoculation of T. vaginalis into mouse peritoneal cavity was performed. Fifteen strains of T. vaginalis were...
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Effects of clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) protein 9 system-Based Deletion of miR-451 in Mouse Embryonic Stem Cells on Their Self-Renewal and Hematopoietic Differentiation

Kim SJ, Kim CH, An B, Ha KS, Hong SH, Kim KS

Pluripotent stem cells (PSCs) are a useful source of cells for exploring the role of genes related with early developmental processes and specific diseases due to their ability to differentiate...
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Studies on the inducing possibility of human visceral larva migrans associated with eating habit of raw liver of domestic animals

Lee KT, Min HK, Chung PR, Chang JK

To observe the possibility of human visceral larva migrans due to eating of raw liver of domestic animals, especially of cattle, and also to serve as a good reference for...
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Recombinant Human Granulocyte Colony-Stimulating Factor Promotes Preinvasive and Invasive Estrogen Receptor-Positive Tumor Development in MMTV-erbB2 Mice

Zhao CL, Zhang GP, Xiao ZZ, Ma ZK, Lei CP, Song SY, Feng YY, Zhao YC, Feng XS

PURPOSE: We investigated whether recombinant human granulocyte colony-stimulating factor (rhG-CSF) could promote the development of preinvasive and invasive breast cancer in mouse mammary tumor virus (MMTV-erbB2) mice with estrogen receptor-positive...
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Influence of transferred anti-Nematospiroides dubius immune serum and IgG on immune reaction in recipient mice

Bang KS

The effect of transferred immune serum and IgG on the response of recipient mice to concurrent infections with larvae has been investigated. Following one infection, recipient mice harboured fewer worms...
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Determining Osteogenic Differentiation Efficacy of Pluripotent Stem Cells by Telomerase Activity

Zhang S, Sun Y, Sui Y, Li Y, Luo Z, Xiao X, Zhou P, Wei S

BACKGROUND: Bone tissue engineering based on pluripotent stem cells (PSCs) is a new approach to deal with bone defects. Protocols have been developed to generate osteoblasts from PSCs. However, the...
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