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Minor BCR-ABL1-Positive Acute Myeloid Leukemia Associated With the NPM1 Mutation and FLT3 Internal Tandem Duplication

Kim MJ, Ahn S, Jeong SH, Jang JH, Han JH, Choi JR, Cho SR

No abstract available.
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Prevalence of FLT3 Internal Tandem Duplication in Adult Acute Myelogenous Leukemia

Lee JN, Kim HR, Shin JH, Joo YD

BACKGROUND: fms-like tyrosine kinase (FLT3), a member of the class III receptor tyrosine kinases, regulates the proliferation and differentiation of hematopoietic stem cells. An internal tandem duplication of the...
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Low Frequency and Variability of FLT3 Mutations in Korean Patients with Acute Myeloid Leukemia

Bang SM, Ahn JY, Park J, Park SH, Park J, Cho EK, Shin DB, Lee JH, Yoo SJ, Jeon IS, Kim YK, Kim HJ, Kim HN, Lee IK, Kang HJ, Shin HY, Ahn HS

FLT3 mutations are common genetic changes, and are reported to have prognostic significance in acute myeloid leukemia (AML). The FLT3 internal tandem duplication (ITD) and the D835 activating mutation in...
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