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Acute and chronic exposure to Tyrophagus putrescentiae induces allergic pulmonary response in a murine model

Nuñez NK, da Cunha A, dos Santos Dutra M, Barbosa GL, Morassutti AL, de Souza R, Vargas MH, Antunes GL, Silveira J, da Silva G, Pitrez PM

BACKGROUND: Tyrophagus putrescentiae (Tp) is a source of aeroallergen that causes allergic diseases. OBJECTIVE: To describe an acute and chronic murine model of allergic asthma with Tp extract with no systemic...
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Respiratory syncytial virus increases eosinophil extracellular traps in a murine model of asthma

Silveira J, Antunes GL, Gassen RB, Breda RV, Stein RT, Pitrez PM, da Cunha A

BACKGROUND: Respiratory viral infections are the leading cause of asthma exacerbations. Eosinophil activation results in the formation of eosinophil extracellular traps (EETs), which release web-like structures of DNA and proteins...
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