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Combination of Magnetic Resonance Spectroscopy and ¹¹C-Methionine Positron Emission Tomography for the Accurate Diagnosis of Non-Enhancing Supratentorial Glioma

Kudulaiti , Qiu T, Lu J, Zhang H, Zhang Z, Guan Y, Zhuang D, Wu J

OBJECTIVE: To evaluate whether the combination of magnetic resonance spectroscopy (MRS) and 11C-methionine positron emission tomography (11C-MET PET) could increase accurate diagnostic sensitivity for non-enhancing supratentorial gliomas. MATERIALS AND METHODS: Between...
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Classical natural ovine scrapie prions detected in practical volumes of blood by lamb and transgenic mouse bioassays

Dassanayake RP, Truscott T, Zhuang D, Schneider , Madsen-Bouterse SA, Young AJ, Stanton JB, Davis WC, O'Rourke K

Scrapie is diagnosed antemortem in sheep by detecting misfolded isoforms of prion protein (PrP(Sc)) in lymphoid follicles of the rectal mucosa and nictitating membranes. Assay sensitivity is limited if (a)...
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