- Dexmedetomidine Attenuates Neuropathic Pain by Inhibiting P2X7R Expression and ERK Phosphorylation in Rats
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Lin JP, Chen CQ, Huang LE, Li NN, Yang Y, Zhu SM, Yao YX
- KMID: 2419336
- Exp Neurobiol.
- 2018 Aug;27(4):267-276.
- doi: 10.5607/en.2018.27.4.267
α2-Adrenoceptor agonists attenuate hypersensitivity under neuropathic conditions. However, the mechanisms underlying this attenuation remain largely unknown. In the present study, we explored the potential roles of purinergic receptor 7 (P2X7R)/extracellular... -
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- Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells
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Zhu SM, Park YR, Seo SY, Kim IH, Lee ST, Kim SW
- KMID: 2465818
- Intest Res.
- 2019 Oct;17(4):527-536.
- doi: 10.5217/ir.2019.00031
BACKGROUND/AIMS: Transforming growth factor-β1 (TGF-β1) induction of epithelial-mesenchymal transition (EMT) is one of the mechanisms by which colorectal cancer (CRC) cells acquire migratory and invasive capacities, and subsequently metastasize. Parthenolide... -
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- Hepatocyte growth factor and soluble cMet levels in plasma are prognostic biomarkers of mortality in patients with severe acute kidney injury
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Li L, An JN, Lee J, Shin DJ, Zhu SM, Kim JH, Kim DK, Ryu DR, Kim S, Lee JP
- KMID: 2524404
- Kidney Res Clin Pract.
- 2021 Dec;40(4):596-610.
- doi: 10.23876/j.krcp.20.258
Background: Hepatocyte growth factor (HGF)/cMet pathway is necessary for repair and regeneration following acute kidney injury (AKI). We evaluated the clinical potential of plasma HGF and soluble cMet as prognostic... -
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