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Abnormal expression of H-Ras induces S-phase arrest and mitotic catastrophe in human T-lymphocyte leukemia

Zamora Dominguez JA, Carrillo IO, Ramos RR, Ramos-Peñafiel CO, Zamudio LJ, Latorre EG, Cruz FC, Tovar AM

Background Leukemia is a neoplasm with high incidence and mortality rates. Mitotic death has been observed in tumor cells treated with chemotherapeutic agents. Ras family proteins participate in the transduction of...
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