- p41-Arc, a regulatory subunit of Arp2/3 complex, can induce premature senescence in the absence of p53 and Rb
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Yun UJ, Park SE, Shin DY
- KMID: 1015457
- Exp Mol Med.
- 2011 Jul;43(7):389-392.
- doi: 10.3858/emm.2011.43.7.042
Cellular senescence is a tumor-suppressive process instigated by proliferation in the absence of telomere replication, by cellular stresses such as oncogene activation, or by activation of the tumor suppressor proteins,... -
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- p53 Prevents Immature Escaping from Cell Cycle G2 Checkpoint Arrest through Inhibiting cdk2-dependent NF-Y Phosphorylation
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Yun UJ, Park HD, Shin DY
- KMID: 2166051
- Cancer Res Treat.
- 2006 Dec;38(4):224-228.
PURPOSE: Recent studies have suggested that p53 regulates the G2 checkpoint in the cell cycle and this function is required for the maintenance of genomic integrity. In this study, we... -
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- Sulfuretin Prevents Obesity and Metabolic Diseases in Diet Induced Obese Mice
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Kim S, Song NJ, Chang SH, Bahn G, Choi Y, Rhee DK, Yun UJ, Choi J, Lee J, Yoo JH, Shin D, Park KM, Kang H, Lee S, Ku JM, Cho YS, Park KW
- KMID: 2432074
- Biomol Ther.
- 2019 Jan;27(1):107-116.
- doi: 10.4062/biomolther.2018.090
The global obesity epidemic and associated metabolic diseases require alternative biological targets for new therapeutic strategies. In this study, we show that a phytochemical sulfuretin suppressed adipocyte differentiation of preadipocytes... -
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