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Evaluating the activity of N-89 as an oral antimalarial drug

Aly NSM, Matsumori H, Dinh TQ, Sato A, Miyoshi Si, Chang KS, Yu HS, Kubota T, Kurosaki Y, Cao DT, Rashed GA, Kim HS

Despite the recent progress in public health measures, malaria remains a troublesome disease that needs to be eradicated. It is essential to develop new antimalarial medications that are reliable and...
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Electroconvulsive Seizure Normalizes Motor Deficits and Induces Autophagy Signaling in the MPTP-Induced Parkinson Disease Mouse Model

Huh S, Yu HS, Kang N, Ahn YM, Kim YS, Kim SH

Objective Electroconvulsive seizure (ECS) is a potent treatment modality for various neuropsychiatric diseases, including Parkinson disease (PD). Recent animal studies showed that repeated ECS activates autophagy signaling, the impairment of...
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Antimalarial effect of synthetic endoperoxide on synchronized Plasmodium chabaudi infected mice

The discovery of new antimalarial drugs can be developed using asynchronized Plasmodium berghei malaria parasites in vivo in mice. Studies on a particular stage are also required to assess the...
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Phylogenetic Characteristics of Fasciola hepatica Isolated from a Korean Patient

Jeong MJ, Park JK, Yu HS

Fascioliasis is a parasitic infection caused by liver flukes. Although several cases have been reported in Korea, phylogenetic analysis of isolates is lacking. In this study, a 66-year-old woman with...
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Trichinella Infection Ameliorated Vincristine-Induced Neuroinflammation in Mice

Jo YR, Park HT, Yu HS, Kong HH

Vincristine (VCR) is a chemotherapeutic agent widely used in treatment of malignancies. However, VCR has a limitation in use since it commonly causes a painful neuropathy (VCR-induced peripheral neuropathy, VIPN)....
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Free-Living Amoeba Vermamoeba vermiformis Induces Allergic Airway Inflammation

Lee DI, Park SH, Kang SA, Kim DH, Kim SH, Song SY, Lee SE, Yu HS

The high percentage of Vermamoeba was found in tap water in Korea. This study investigated whether Vermamoeba induced allergic airway inflammation in mice. We selected 2 free-living amoebas (FLAs) isolated...
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Comparison of soft tissue changes between incisor tipping and translation after premolar extraction

Baik W, Choi SH, Cha JY, Yu HS, Lee KJ

Objective: This study compared soft tissue changes after extraction of the four premolars followed by maximum retraction of the anterior teeth according to the type of anterior teeth movement: tipping...
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Trends in End-of-Life Resource Utilization and Costs among Prostate Cancer Patients from 2006 to 2015: A Nationwide Population-Based Study

Ha YS, Kim SY, Chung JI, Choi H, Kim JH, Yu HS, Cho IC, Kim HJ, Chung HC, Koh JS, Lee JY, Park DJ, Kim HT, Yoo ES, Kwon TG, Min K, Kim WJ, Yun SJ, Park JH

Purpose:The purpose of this study was to evaluate end-of-life resource utilization and costs for prostate cancer patients during the last year of life in Korea. Materials and Methods:The study used the...
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Phylogenetic Positioning of a Strongyloides stercoralis Isolate Recovered from a Korean Patient and Comparison with Other Asian Isolates

Bae J, Jeong MJ, Shin Dh, Kim HW, Ahn SH, Choi JH, Yu HS

Strongyloidiasis is caused by Strongyloides stercoralis and is one of the most neglected tropical diseases in tropical and subtropical regions. Although several strongyloidiasis cases have been reported in Korea, genetic...
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Stability of bimaxillary surgery involving intraoral vertical ramus osteotomy with or without presurgical miniscrew-assisted rapid palatal expansion in adult patients with skeletal Class III malocclusion

Ahn YS, Choi SH, Lee KJ, Jung YS, Baik HS, Yu HS

Objective: The aim of this study was to evaluate the stability of bimaxillary surgery involving bilateral intraoral vertical ramus osteotomy performed with or without presurgical miniscrew-assisted rapid palatal expansion (MARPE)...
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Anti-staphylococcal Effect of a Nephrite-containing Contact Lens Storage Case

Park SH, Lee SU, Kim YK, Yu HS, Park SH, Ahn JH, Kim SJ, Shin JH, Lee JE

Purpose: To compare the anti-staphylococcal effect of nephrite-containing contact lens (CL) storage cases and conventional CLstorage cases. Method: The degree of proliferation and adhesion of Staphylococcus aureus (S. aureus) on first-...
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Phylogenetic Characteristics of Echinococcus granulosus Sensu Lato in Uzbekistan

Kim HJ, Yong TS, Shin MH, Lee KJ, Park GM, Suvonkulov U, Kovalenko , Yu HS

Echinococcosis occurs mainly in areas with heavy livestock farming, such as Central Asia, America, and Australia. Echinococcus granulosus sensu lato (s.l.) infection causes echinococcosis in intermediate hosts, such as sheep,...
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Identification of Free-Living Amoebas in Tap Water of Buildings with Storage Tanks in Korea

Lee DI, Park SH, Baek JH, Yoon JW, Jin SI, Han KE, Yu HS

Free-living amoebas (FLAs) can cause severe disease in humans and animals when they become infected. However, there are no accurate survey reports on the prevalence of FLAs in Korea. In...
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Comparison of surgical outcomes between lateral and posterior approaches for retroperitoneal laparoscopic adrenalectomy: A single surgeon's experience

Oh JY, Chung HS, Yu SH, Kim MS, Yu HS, Hwang EC, Oh KJ, Kim SO, Jung SI, Kang TW, Park K, Kwon D

PURPOSE: To compare surgical outcomes between the lateral and the posterior approach for retroperitoneal laparoscopic adrenalectomy (RLA). MATERIALS AND METHODS: We retrospectively reviewed the records of 130 patients who underwent RLA...
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Comparison of three midsagittal planes for three-dimensional cone beam computed tomography head reorientation

Lee EH, Yu HS, Lee KJ, Han SS, Jung HD, Hwang CJ

OBJECTIVE: This study compared three prominent midsagittal planes (MSPs) to identify the MSP that best approximates the true symmetrical MSP. METHODS: Forty-three patients (mean age, 23.0 ± 8.20 years) were grouped...
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A Prospective, Multicenter, Open-Label Study of Dose Escalation Therapy in Male Patients With Nocturia Refractory to 0.2-mg Tamsulosin Monotherapy

Yu HS, Lee JW, Yu J, Cho MC, Cho SY

PURPOSE: To investigate the efficacy and safety of 0.4 mg of tamsulosin in patients with nocturia not responding to 0.2 mg. METHODS: Patients with intractable nocturia after treatment with 0.2 mg...
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Three-dimensional comparison of 2 digital models obtained from cone-beam computed tomographic scans of polyvinyl siloxane impressions and plaster models

Park JY, Kim D, Han SS, Yu HS, Cha JY

PURPOSE: This study was performed to evaluate the dimensional accuracy of digital dental models constructed from cone-beam computed tomographic (CBCT) scans of polyvinyl siloxane (PVS) impressions and cast scan models. MATERIALS...
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Effect of archwire stiffness and friction on maxillary posterior segment displacement during anterior segment retraction: A three-dimensional finite element analysis

Park CS, Yu HS, Cha JY, Mo SS, Lee KJ

OBJECTIVE: Sliding mechanics using orthodontic miniscrews is widely used to stabilize the anchorage during extraction space closure. However, previous studies have reported that both posterior segment displacement and anterior segment...
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Predictors of midpalatal suture expansion by miniscrew-assisted rapid palatal expansion in young adults: A preliminary study

Shin H, Hwang CJ, Lee KJ, Choi YJ, Han SS, Yu HS

OBJECTIVE: We sought to determine the predictors of midpalatal suture expansion by miniscrew-assisted rapid palatal expansion (MARPE) in young adults. METHODS: The following variables were selected as possible predictors: chronological age,...
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Prevalence of Intestinal Helminth Infections in Dogs and Two Species of Wild Animals from Samarkand Region of Uzbekistan

Yong TS, Lee KJ, Shin MH, Yu HS, Suvonkulov U, Sergeevich TB, Shamsiev A, Park GM

This study aimed to determine the prevalence of intestinal helminth parasitic infections and associated risk factors for the human infection among the people of Samarkand, Uzbekistan. Infection status of helminths...
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