- Surveillance of resistant pathogens and rational use of antibiotics: general remarks
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Acar JF
- KMID: 711588
- Yonsei Med J.
- 1998 Dec;39(6):485-487.
- doi: 10.3349/ymj.1998.39.6.485
Surveillance of resistant pathogens should lead to improved treatment of patients and to a rational use of antibiotics. The process for decision making between microbiology, general practice and health policy... -
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- Antibiotic use at a pediatric age
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Kim DS, Park MS
- KMID: 711603
- Yonsei Med J.
- 1998 Dec;39(6):595-603.
- doi: 10.3349/ymj.1998.39.6.595
For infections in infants and children, the successful antibiotic treatment depends primarily on rapid diagnosis of the disease, identification of pathogenic microorganisms, and appropriate application of specialized pharmacokinetic and pharmacodynamic... -
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- Antimicrobial resistance patterns of Bacteroides fragilis group organisms in Korea
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Lee K, Shin HB, Chong Y
- KMID: 711601
- Yonsei Med J.
- 1998 Dec;39(6):578-586.
- doi: 10.3349/ymj.1998.39.6.578
Antimicrobial resistance patterns of 913 clinical isolates of Bacteroides fragilis group organisms were monitored during an 8-year period in Korea. In general the resistance rates of the non-fragilis B. fragilis... -
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- Antimicrobial resistance in enterococci
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Pai CH, Kim MN
- KMID: 711598
- Yonsei Med J.
- 1998 Dec;39(6):554-561.
- doi: 10.3349/ymj.1998.39.6.554
Enterococci have emerged as a major nosocomial pathogen and as an ever-increasing problem in antimicrobial resistance. They are ubiquitous in the intestinal flora of humans and animals and inherently resistant... -
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- Nocardia osteomyelitis in a pachymeningitis patient: an example of a difficult case to treat with antimicrobial agents
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Shin KH, Lee WS, Son YK, Lee K, Chong Y
- KMID: 711604
- Yonsei Med J.
- 1998 Dec;39(6):604-610.
- doi: 10.3349/ymj.1998.39.6.604
Antimicrobial agents played a miraculous role in the treatment of bacterial infections until resistant bacteria became widespread. Besides antimicrobial-resistant bacteria, many factors can influence the cure of infection. Nocardia infection... -
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- Acquisition of methicillin resistance and progression of multiantibiotic resistance in methicillin-resistant Staphylococcus aureus
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Ito T, Hiramatsu
- KMID: 711594
- Yonsei Med J.
- 1998 Dec;39(6):526-533.
- doi: 10.3349/ymj.1998.39.6.526
Methicillin-resistant Staphylococcus aureus (MRSA) produces specific penicillin-binding protein, PBP2', which shows remarkably low affinities to most beta-lactam antibiotics except those such as penicillin G and ampicillin. The region surrounding mecA... -
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- Plasmid-encoded AmpC beta-lactamases: how far have we gone 10 years after the discovery?
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Bauernfeind A, Chong Y, Lee K
- KMID: 711593
- Yonsei Med J.
- 1998 Dec;39(6):520-525.
- doi: 10.3349/ymj.1998.39.6.520
The dogma that ampC genes are located exclusively on the chromosome was dominant until about 10 years ago. Since 1989 over 15 different plasmid-encoded AmpC beta-lactamases have been reported from... -
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- Use of vaccine in the era of antimicrobial resistance: need of effective pneumococcal vaccines
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Sohn YM
- KMID: 711605
- Yonsei Med J.
- 1998 Dec;39(6):611-618.
- doi: 10.3349/ymj.1998.39.6.611
Streptococcus pneumoniae is an important pathogen causing invasive infections particularly in children. Penicillin-nonsusceptible pneumococci are very prevalent in Korea and a difficult problem in antimicrobial treatment. Immunization with effective vaccines... -
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- Current susceptibility patterns of anaerobic bacteria
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Wexler HM, Finegold S
- KMID: 711590
- Yonsei Med J.
- 1998 Dec;39(6):495-501.
- doi: 10.3349/ymj.1998.39.6.495
While antibiotic resistance among anaerobes continues to increase, the frequency of antimicrobial susceptibility testing for anaerobes is declining. Because anaerobic infections are often mixed and detailed bacteriology of the organisms... -
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- Vancomycin-resistant enterococcal infections in Korea
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Kim JM, Song YG
- KMID: 711599
- Yonsei Med J.
- 1998 Dec;39(6):562-568.
- doi: 10.3349/ymj.1998.39.6.562
Enterococci recently became the second-to-third most commonly isolated organism from nosocomial infections. Enterococci are intrinsically more resistant to many antimicrobial agents and often show acquired resistance to many antimicrobial agents... -
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- Emergence and spread of antimicrobial resistance of Streptococcus pneumoniae in Korea
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Song JH
- KMID: 711597
- Yonsei Med J.
- 1998 Dec;39(6):546-553.
- doi: 10.3349/ymj.1998.39.6.546
Pneumococcal resistance has become a global issue during the past three decades. One of the major foci of pneumococcal resistance worldwide is the Asian region including Korea, Japan, and Hong... -
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- A mutation in QRDR in the ParC subunit of topoisomerase IV was responsible for fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae
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Choi H, Lee HJ, Lee Y
- KMID: 711596
- Yonsei Med J.
- 1998 Dec;39(6):541-545.
- doi: 10.3349/ymj.1998.39.6.541
Forty-one strains of Streptococcus pneumoniae were isolated at Seoul National University Children's Hospital from 1991 to 1997. Isolates were divided into six groups based on MICs of three quinolones, ciprofloxacin,... -
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- The characteristics of extended-spectrum beta-lactamases in Korean isolates of Enterobacteriaceae
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Pai H
- KMID: 711592
- Yonsei Med J.
- 1998 Dec;39(6):514-519.
- doi: 10.3349/ymj.1998.39.6.514
Extended-spectrum beta-lactamases (ESBLs) in gram-negative organisms have been implicated as the enzymes responsible for resistance to oxyimino-cephalosporins. The incidence of ESBL- producers in Korean isolates of Escherichia coli and Klebsiella... -
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- Why do antimicrobial agents become ineffectual?
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Inoue M, Kuga A, Shimauchi , Yano H, Okamoto R
- KMID: 711591
- Yonsei Med J.
- 1998 Dec;39(6):502-513.
- doi: 10.3349/ymj.1998.39.6.502
Antibiotic resistance has evolved over the past 50 years from a merely microbiological curiosity to a serious medical problem in hospitals all over the world. Resistance has been reported in... -
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- Korean Nationwide Surveillance of Antimicrobial Resistance of bacteria in 1997
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Chong Y, Lee K, Park YJ, Jeon DS, Lee MH, Kim MY, Chang CH, Kim EC, Lee NY, Kim HS, Kang ES, Cho HC, Paik IK, Lee HS, Jang SJ, Park AJ, Cha YJ, Kang SH, Lee MH, Song W, Shin JH
- KMID: 711600
- Yonsei Med J.
- 1998 Dec;39(6):569-577.
- doi: 10.3349/ymj.1998.39.6.569
Antimicrobial-resistant bacteria are known to be prevalent in tertiary-care hospitals in Korea. Twenty hospitals participated to this surveillance to determine the nationwide prevalence of resistance bacteria in 1997. Seven per... -
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- Bacterial resistance to antimicrobial agents: an overview from Korea
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Kim WJ, Park SC
- KMID: 711589
- Yonsei Med J.
- 1998 Dec;39(6):488-494.
- doi: 10.3349/ymj.1998.39.6.488
Antimicrobial resistance of bacteria has become a worldwide problem. Available data suggest that the resistance problem is comparatively more serious in Korea. In large hospitals, the proportion of methicillin-resistant Staphylococcus... -
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- Molecular analysis of fluoroquinolone-resistance in Escherichia coli on the aspect of gyrase and multiple antibiotic resistance (mar) genes
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Park YH, Yoo JH, Huh DH, Cho YK, Choi JH, Shin WS
- KMID: 711595
- Yonsei Med J.
- 1998 Dec;39(6):534-540.
- doi: 10.3349/ymj.1998.39.6.534
We analyzed the fluoroquinolone resistance mechanism of 28 isolates of ciprofloxacin-resistant E. coli from patients who received ciprofloxacin as a regimen of a selective gut decontamination. Isolates distinctive by infrequent... -
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- Epidemiological typing of methicillin-resistant Staphylococcus aureus outbreak isolates by pulsed-field gel electrophoresis and antibiogram
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Kim EC, Jung HJ, Oh MD, Lee HJ, Oh HS, Choe KW
- KMID: 711602
- Yonsei Med J.
- 1998 Dec;39(6):587-594.
- doi: 10.3349/ymj.1998.39.6.587
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common nosocomial pathogens. In April 1997, there were five MRSA-infected patients among 16 patients in the Neonatal Intensive Care Unit (NICU),... -
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