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A novel photonumeric hand grading scale for hand rejuvenation

Lee JH, Choi YS, Park ES, Kim JS, Kang MS, Oh HY, Yang SD, Jeon SH

BACKGROUND: Few scales are currently available to evaluate changes in hand volume. We aimed to develop a hand grading scale for quantitative assessments of dorsal hand volume with additional consideration...
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Epigenetic modification of α-N-acetylgalactosaminidase enhances cisplatin resistance in ovarian cancer

Ha YN, Sung HY, Yang SD, Chae YJ, Ju W, Ahn JH

Although cisplatin is one of the most effective antitumor drugs for ovarian cancer, the emergence of chemoresistance to cisplatin in over 80% of initially responsive patients is a major barrier...
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Aberrant epigenetic regulation of GABRP associates with aggressive phenotype of ovarian cancer

Sung HY, Yang SD, Ju W, Ahn JH

Metastasis is a major cause of therapeutic failure in ovarian cancer. To elucidate molecular mechanisms of ovarian cancer metastasis, we previously established a metastatic xenograft mouse model using human ovarian...
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Down syndrome with asymptomatic neuroglial cyst: A case report and review of the literature

Yang SD, Lee SJ, Lee DH, Hong YH

Down syndrome (DS, trisomy 21) is associated with neuroanatomical abnormalities, including choroid plexus cysts and various types of brain tumors. Trisomy 21 is associated with oncogenic factor, especially in brain...
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Aberrant Hypomethylation of Solute Carrier Family 6 Member 12 Promoter Induces Metastasis of Ovarian Cancer

Sung HY, Yang SD, Park AK, Ju W, Ahn JH

PURPOSE: Ovarian cancer (OC) is the most fatal of gynecological malignancies with a high rate of recurrence. We aimed to evaluate the expression of solute carrier family 6, member 12...
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Estimation of Prognostic Marker Genes by Public Microarray Data in Patients with Ovarian Serous Cystadenocarcinoma

Yang SD, Jang SS, Han JA, Park HS, Kim JI

PURPOSE: Lymphatic invasion (LI) is regarded as a predictor of the aggressiveness of ovarian cancer (OC). However, LI is not always the major determinant of long-term patient survival. To establish...
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Genome-Wide Association Study of Bone Mineral Density in Korean Men

Bae YS, Im SW, Kang MS, Kim JH, Lee SH, Cho BL, Park JH, Nam YS, Son HY, Yang SD, Sung J, Oh KH, Yun JM, Kim JI

Osteoporosis is a medical condition of global concern, with increasing incidence in both sexes. Bone mineral density (BMD), a highly heritable trait, has been proven a useful diagnostic factor in...
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J2.5dPathway: A 2.5D Visualization Tool to Display Selected Nodes in Biological Pathways, in Parallel Planes

Ham SI, Song EH, Yang SD, Thong CT, Rhie A, Galbadrakh B, Lee KE, Park HS, Lee SH

  • KMID: 1469578
  • Genomics Inform.
  • 2009 Sep;7(3):171-174.
The characteristics of metabolic pathways make them particularly amenable to layered graph drawing methods. This paper presents a visual Java-based tool for drawing and annotating biological pathways in twoand- a-half...
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A Computer-aided Design Tool with Semiautomatic Image-Processing Features for Visualizing Biological Pathways

Ham SI, Yang SD, Thong CT, Park HS

  • KMID: 1469577
  • Genomics Inform.
  • 2009 Sep;7(3):168-170.
The explosion in biological data resulting from highthroughput experiments requires new software tools to manipulate and display pathways in a way that can integrate disparate sources of information. A visual...
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Individualized Ideal Occlusal Plane for Orthognathic Surgery and Orthodontic Treatment (Preliminary Study)

Hwang YJ, Yang SD, Choi JY

  • KMID: 2186628
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2009 Mar;31(2):143-148.
INTRODUCTION: To correct abnormal occlusal plane by orthognathic surgery, we need to have clear criteria for therapeutic occlusal plane. Authors introduced the concept of individualized ideal occlusal plane(Yplane), which is...
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A Case of Intracranial and Extradural Cholesterol Granuloma

Oh JK, Yang SD, Moon SY, Shin SO

Cholesterol granuloma is a histological term used for the description of a tissue response to a foreign body such as cholesterol crystals. The pathogenesis of cholesterol granuloma is controversial. But...
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Clinical Characteristics and Treatment Results of Sudden Deafness in Children

Moon YE, Yang SD, Choi JC, Kim MS, Oh JK, Kim HA, Kim DH, Shin SO

BACKGROUND AND OBJECTIVES: Sudden deafness, an important disease characterized by abrupt sensorineural hearing loss, is rare in children and the prognosis in children is accepted to be worse than that...
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J2dpathway: A Global Metabolic Pathway Viewer with Node-Abstracting Features

Song EH, Ham SI, Yang SD, Rhie A, Park HS, Lee SH

  • KMID: 2166341
  • Genomics Inform.
  • 2008 Jun;6(2):68-71.
The static approach of representing metabolic pathway diagrams offers no flexibility. Thus, many systems adopt automatic graph layout techniques to visualize the topological architecture of pathways. There are weaknesses, however,...
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Refactoring the Code for Visualizing Protein Database Information in a 3D Viewer for Software Reusability

Chun YJ, Ham SI, Yang SD, Rhie A, Park HS

  • KMID: 2166322
  • Genomics Inform.
  • 2008 Mar;6(1):50-53.
We have released five Java Application Programming Interface (API) packages for viewing three-dimensional structures of proteins from the Protein Data Bank. To this end, the user interface of an earlier...
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A Study on Preparation of 3'-[18F]Fluoro-3'-deoxythymidine and Its Biodistribution in 9L Glioma Bearing Rats

Shim AY, Moon BS, Lee TS, Lee KC, An GI, Yang SD, Yu KH, Cheon GJ, Choi CW, Lim SM, Chun KS

  • KMID: 1512526
  • Nucl Med Mol Imaging.
  • 2006 Oct;40(5):263-270.
PURPOSE: Several radioisotope-labeled thymidine derivatives such as [11C]thymidine was developed to demonstrate cell proliferation in tumor. But it is difficult to track metabolism with [11C]thymidine due to rapid in vivo...
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In vivo targeting of ERGpotassiumchannels inmice and dogs by a positron-emitting analogue of fluoroclofilium

Kim SW, Yang SD, Ahn BJ, Park JH, Lee DS, Gessner G, Heinemann , Herdering , Yu KH

  • KMID: 1093461
  • Exp Mol Med.
  • 2005 Aug;37(4):269-275.
The antiarrhythmic clofilium is an efficient blocker of hERG1 potassium channels that are strongly expressed in the heart. Therefore, derivatives of clofilium that emit positrons might be useful tools for...
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Two-jaw surgery by use of Surgical Jaw Relator

Yang SD

  • KMID: 1923978
  • Korean J Orthod.
  • 2005 Jun;35(3):238-249.
The contemporary two-jaw surgical approach usually involves a Le Fort osteotomy of the maxilla and a ramal osteotomy of the mandible with 3-dimensional repositioning of the jaws as well as...
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Fabrication of surgical splint by using of surgical jaw relator

Yang SD

  • KMID: 2183822
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2005 Mar;27(2):188-195.
After making the surgical treatment plan, the surgical movements are duplicated in the model surgery. During this procedure, reference points and lines are drawn on the base of the...
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Increased Plasma Dipeptidyl Peptidase IV Activities in ob/ob Mice

Rhee SD, Lee YS, Lee HS, Jung WH, Cheon HG, Ahn JH, Kim SS, Paik SG, Yang SD

  • KMID: 2177801
  • J Korean Diabetes Assoc.
  • 2005 Jan;29(1):22-29.
BACKGROUND: Dipeptidyl peptidase IV (DPP IV/CD26), a multi-functional glycoprotein, cleaves and inactivates major insulinotropic hormones, such as glucagon-like protein (GLP)-1 and glucose dependent insulinotrophic polypeptide (GIP). METHODS: The plasma DPP...
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Characteristics of the Newly Established Diabetic Model Mice, TallyHo

Rhee SD, Jeong WH, Sung YY, Lee HS, Lee KB, Kim HY, Yang SD

  • KMID: 1575479
  • J Korean Diabetes Assoc.
  • 2004 Jun;28(3):177-186.
BACKGROUND: TallyHo(TH) mice are a newly established model for non-insulin dependent diabetes mellitus(NIDDM), for polygenic causative genes that have not yet been identified. It has been reported that TH mice...
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