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Familial aggregation of inflammatory bowel disease in patients with ulcerative colitis

Gupta A, Bopanna S, Kedia S, Yadav DP, Goyal S, Jain S, Makharia G, Ahuja V

BACKGROUND/AIMS: Familial occurrence of inflammatory bowel disease (IBD) is well documented. Reports from Western countries have shown a higher familial occurrence of ulcerative colitis (UC) in first- and second-degree relatives...
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Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study

Jain S, Kedia S, Bopanna S, Yadav DP, Goyal S, Sahni P, Pal S, Dash NR, Makharia G, Travis SP, Ahuja V

BACKGROUND/AIMS: Truelove and Witts criteria have been used to define acute severe colitis since the 1950s. However, hemoglobin (an additional criterion of the definition) levels in the general population in...
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Role of random biopsies in surveillance of dysplasia in ulcerative colitis patients with high risk of colorectal cancer

Bopanna S, Roy M, Das P, Dattagupta S, Sreenivas , Mouli VP, Kedia S, Dhingra R, Pradhan R, Kumar NS, Yadav DP, Makharia G, Ahuja V

BACKGROUND/AIMS: Recent data suggest that the incidence of ulcerative colitis (UC) related colorectal cancer (CRC) in India is similar to that of West. The optimum method for surveillance is still...
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High risk of tuberculosis during infliximab therapy despite tuberculosis screening in inflammatory bowel disease patients in India

Agarwal A, Kedia S, Jain S, Gupta V, Bopanna S, Yadav DP, Goyal S, Mouli VP, Dhingra R, Makharia G, Ahuja V

BACKGROUND/AIMS: The data on the risk of tuberculosis (TB) reactivation with infliximab (IFX) in patients with inflammatory bowel disease (IBD) from TB endemic countries, like India, is limited. The risk...
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Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis

Kedia S, Sharma R, Sreenivas , Madhusudhan KS, Sharma V, Bopanna S, Pratap Mouli V, Dhingra R, Yadav DP, Makharia G, Ahuja V

Abdominal computed tomography (CT) can noninvasively image the entire gastrointestinal tract and assess extraintestinal features that are important in differentiating Crohn's disease (CD) and intestinal tuberculosis (ITB). The present meta-analysis...
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