- Pazopanib as a second line treatment for uterine and ovarian carcinosarcoma: a single institutional study
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Nishikawa , Hasegawa K, Yabuno A, Yoshida H, Yasuda M, Kozawa E, Fujiwara K
- KMID: 2413861
- J Gynecol Oncol.
- 2017 Jan;28(1):e25.
- doi: 10.3802/jgo.2017.28.e25
No abstract available. -
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- Evaluation of Circulating Tumor DNA in Patients with Ovarian Cancer Harboring Somatic PIK3CA or KRAS Mutations
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Ogasawara A, Hihara T, Shintani D, Yabuno A, Ikeda Y, Tai K, Fujiwara K, Watanabe K, Hasegawa K
- KMID: 2507947
- Cancer Res Treat.
- 2020 Oct;52(4):1219-1228.
- doi: 10.4143/crt.2019.688
Purpose Circulating tumor DNA (ctDNA) is an attractive source for liquid biopsy to understand molecular phenotypes of a tumor non-invasively, which is also expected to be both a diagnostic and prognostic... -
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- High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo
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Ikeda Y, Sato S, Yabuno A, Shintani D, Ogasawara A, Miwa M, Zewde M, Miyamoto T, Fujiwara K, Nakamura Y, Hasegawa K
- KMID: 2512058
- J Gynecol Oncol.
- 2020 Nov;31(6):e93.
- doi: 10.3802/jgo.2020.31.e93
Objective: Maternal embryonic leucine zipper kinase (MELK) is receiving an attention as a therapeutic target in various types of cancers. In this study, we aimed to evaluate the prognostic significance... -
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- Randomized phase III trial comparing pegylated liposomal doxorubicin (PLD) at 50 mg/m2 versus 40 mg/m2 in patients with platinum-refractory and -resistant ovarian carcinoma: the JGOG 3018 Trial
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Motohashi T, Yabuno A, Michimae H, Ohishi T, Nonaka M, Takano M, Nishio S, Fujiwara H, Keiichi K, Kondo E, Sugiyama T, Tabata T
- KMID: 2526299
- J Gynecol Oncol.
- 2021 Jan;32(1):e9.
- doi: 10.3802/jgo.2021.32.e9
Objective: The standard dose for pegylated liposomal doxorubicin (PLD) is 50 mg/m2 every 4 weeks. While 40 mg/m2 has recently been used in clinical practice, evidence supporting this use remains... -
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