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Interleukin-1beta Modulates Proliferation, Interleukin-6 and Interleukin Receptor Expression in PC-3 and DU-145 Prostatic Cancer Cells

Myung SC, Ahn SY, Oh SY, Won EH, Park ES, Kim KD

  • KMID: 2293512
  • Korean J Urol.
  • 2004 Aug;45(8):810-816.
Purpose: IL-1 is a multifunctional proinflammatory cytokine. As the proliferative effects of IL-6 and IL-6 receptor expressions on prostatic cancer cells in response to IL-1 have not been determined, the...
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The Effects of Selective Cyclooxygenase-2 Inhibitor and Prostaglandin E2 Receptor Agonists on the Endothelin Axis of Prostate Cancer Cells

Kim TH, Kim YS, Myung SC, Lee SW, Won EH, Kim TH

PURPOSE: The enhanced expression of the cyclooxygenase-2 (COX-2), prostaglandin E2 receptor (EPs) and endothelin-1 (ET-1) axis is known to play a significant role in the development and progression of several...
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Prostagladin E Receptor II and IV Increase the Expression of Martrix Metalloproteinase-7 in PC (Prostate Cancer)-3 Cells

Kim TH, Kim YS, Myoung SC, Lee JH, Won EH

  • KMID: 2293493
  • Korean J Urol.
  • 2004 May;45(5):478-484.
PURPOSE: The effects of PGE2 receptors (EP1, 2, 3, 4) on the proliferation of prostate cancer cells are still unclear. The degradation of the basement membrane by MMP-2, 7, 9...
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Induction of CEA-specific Cytotoxic T Lymphocytes by Murine Dendritic Cells Expressing CEA

Won EH, Kim CH, Park MY, Cho HI, Oh ST, Hong YK, Kim TG

BACKGROUND: Carcinoembryonic antigen (CEA) is well-known soluble tumor marker frequently detectable in peripheral blood of carcinoma patients and considered as good target for antigen-specific immunotherapy. In this study, we used...
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Effects of Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF) on the Interleukin-6 Expression in the Prostate Cancer Cell Line PC-3

Kang GH, Myung SC, Kim TH, Oh SY, Won EH, Kim SC, Kim WS, Kim YS

PURPOSE: Interleukin-6 (IL-6) can stimulate a variety of tumors including prostatic carcinoma. Research has recently shown that IL-6 may act to stimulate the progression of prostatic cancer. IL-6 is elevated...
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The Prostaglandin E Receptor Agonists Increase Granulocyte Macrophage Colony-Stimulating Factor in Prostate Cancer Cells

Kim TH, Kim YS, Myung SC, Lee DH, Won EH, Lee SY

  • KMID: 2293239
  • Korean J Urol.
  • 2004 Dec;45(12):1272-1278.
PURPOSE: The predilection for prostate carcinoma cells to metastasize to bone suggests the hypothesis that bone and/or bone marrow-derived factors may promote prostate carcinoma cell growth and/or their survival. To...
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