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Ustekinumab is effective in biological refractory Crohn's disease patients–regardless of approval study selection criteria

Saman S, Goetz M, Wendler J, Malek NP, Wehkamp J, Klag T

BACKGROUND/AIMS: Ustekinumab is effective in active Crohn's disease. In a retrospective study, we assessed the clinical outcome in nonresponders to anti-tumor necrosis factor therapy, and/or conventional therapy and/or the α4β7-integrin...
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